Preparation of 31Si-labelled silicate:: a radiotracer for silicon studies in biosystems

被引：2

作者：

Brasser, H. J. ^{[1
]}

Gurboga, G. ^{[1
]}

Kroon, J. J. ^{[1
]}

Kolar, Z. I. ^{[1
]}

Wolterbeek, H. T. ^{[1
]}

Volkers, K. J. ^{[1
]}

Krijger, G. C. ^{[1
]}

机构：

[1] Delft Univ Technol, Fac Sci Appl, Dept Radiat Radionuclides & Reactors, NL-2629 JB Delft, Netherlands

来源：

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 2006年 / 49卷 / 10期

关键词：

Si-31; P-32; no-carrier added; production;

D O I：

10.1002/jlcr.1096

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

No-carrier-added Si-31 was produced by P-31(n,P)Si-31 in the nuclear reactor of the Delft University of Technology. Several methods were investigated to remove the side product P-32, and the chemical form of Si-31 was investigated. All methods except one gave good results. Anion exchange with Dowex resin gave the best results in activity concentration (3.8 x 10(6) Bq/ml, with only 3.2 x 10(3) Bq/ml P-32 as by-product) and specific activity (A(s) > 17 TBq/g). The product is suitable for biological systems. Copyright (c) 2006 John Wiley & Sons, Ltd.

引用

页码：867 / 882

页数：16

共 28 条

[1] DISTRIBUTION OF SILICON-31-LABELED SILICIC-ACID IN THE RAT [J].