New withanolides from fresh berries of Withania somnifera

被引：40

作者：

Lal, Payare

Misra, Laxminarain ^{[1
]}

Sangwan, Rajender S.

Tuli, Rakesh

机构：

[1] Cent Inst Med & Aromat Plants, Lucknow 226015, Uttar Pradesh, India

[2] Natl Bot Res Inst, Lucknow 226001, Uttar Pradesh, India

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2006年 / 61卷 / 09期

关键词：

Solanaceae; Withania somnifera; steroids; withasteroids; ashwagandha; berries;

D O I：

10.1515/znb-2006-0914

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The chloroform extract of the fresh berries of Withania somnifera has been investigated to afford stigmasterol, its glucoside, withanone, 27-hydroxy withanolide A along with two new with-anolides, namely, iso-withanone (1) and 6 alpha,7 alpha-epoxy-1 alpha,30,5 alpha-trihydroxy-witha-24-enolide (2). Compound 1 possesses an uncommon 17 alpha-oriented side chain whereas compound 2 has 1 alpha,3 beta-dihydroxy group which is a molecule of biogenetic significance for withasteroids.

引用

页码：1143 / 1147

页数：5

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