Prospective study on factors affecting the prognosis of oral cancer in a Chinese population

被引：34

作者：

Liu, Fengqiong

Chen, Fa

Huang, Jiangfeng

Yan, Lingjun

Liu, Fangping

Wu, Junfeng

Qiu, Yu

Zheng, Xiaoyan

Zhang, Rongzhao

Lin, Lisong

He, Baochang ^{[1
]}

机构：

[1] Fujian Med Univ, Sch Publ Hlth, Dept Epidemiol & Hlth Stat, Fujian Prov Key Lab Environm Factors & Canc, Fujian, Peoples R China

[2] Fujian Med Univ, Affiliated Hosp 1, Dept Stomatol, Fujian, Peoples R China

来源：

ONCOTARGET | 2017年 / 8卷 / 03期

关键词：

oral cancer; prognosis; BMI; chemotherapy; radiotherapy; SQUAMOUS-CELL CARCINOMA; GASTRIC-CANCER; NECK-CANCER; SOCIODEMOGRAPHIC FACTORS; SOCIOECONOMIC-STATUS; CAVITY CANCER; LOCAL-CONTROL; SURVIVAL; HEAD; SURGERY;

D O I：

10.18632/oncotarget.13842

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This study was performed to identify the factors affecting prognosis of oral cancer patients. 1240 pathologically confirmed oral cancer patients were included. The sociodemographic and clinical characteristics of all patients were collected. Univariate and multivariate Cox proportional hazards models were used to assess potential prognostic factors for survival. 1240 oral cancer patients were followed up for 49235.00 person months, and the 5-year overall survival rate was 64.38%. Both univariate and multivariate Cox regression analysis indicated that Body Mass Index < 18.5 kg/m(2) (vs 18.5-23.9 kg/m(2)), age >= 55 years (vs < 55 years), clinical stages of II-IV (vs stage I), and poor differentiation (vs well differentiation) were associated with worse survival of oral cancer patients. While surgery (vs non-surgery) and origin of urban area (vs rural area) were protective factors. However, no significant association was found between adjuvant therapy and survival in oral cancer patients.

引用

页码：4352 / 4359

页数：8

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