Brown Fat in Humans: Consensus Points and Experimental Guidelines

被引：113

作者：

Cypess, Aaron M. ^{[1
]}

Haft, Carol R. ^{[2
]}

Laughlin, Maren R. ^{[2
]}

Hu, Houchun H. ^{[3
]}

机构：

[1] Harvard Univ, Sch Med, Joslin Diabet Ctr, Div Res, Boston, MA 02215 USA

[2] NIDDK, NIH, Bethesda, MD 20892 USA

[3] Childrens Hosp Los Angeles, Dept Radiol, Los Angeles, CA 90027 USA

来源：

CELL METABOLISM | 2014年 / 20卷 / 03期

关键词：

ADIPOSE-TISSUE THERMOGENESIS; ADULT HUMANS; SUPRACLAVICULAR REGION; ENERGY-EXPENDITURE; BLOOD-FLOW; COLD; ACTIVATION; TEMPERATURE; METABOLISM; ADIPOGENESIS;

D O I：

10.1016/j.cmet.2014.07.025

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

As part of a current worldwide effort to understand the physiology of human BAT (hBAT) and whether its thermogenic activity can be manipulated to treat obesity, the workshop "Exploring the Roles of Brown Fat in Humans'' was convened at the National Institutes of Health on February 25-26, 2014. Presentations and discussion indicated that hBAT and its physiological roles are highly complex, and research is needed to understand the health impact of hBAT beyond thermogenesis and body weight regulation, and to define its interactions with core physiological processes like glucose homeostasis, cachexia, physical activity, bone structure, sleep, and circadian rhythms.

引用

页码：408 / 415

页数：8

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