A general route to 4-imidazolyl-containing multidentate ligands for biomimetic studies

被引：13

作者：

Collman, JP ^{[1
]}

Zhong, M ^{[1
]}

Wang, Z ^{[1
]}

机构：

[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 06期

关键词：

D O I：

10.1021/ol990201b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] 4-Iodo-1-tritylimidazole undergoes magnesium-iodine exchange with a Grignard reagent to give selectively the 4-magnesioimidazole derivative, which reacts with esters to form a variety of poly-4-imidazolyl carbinol compounds in 40-79% yields. A wide range of bi-, tri-, and pentadentate ligands featuring 4-substituted imidazole units have been efficiently synthesized.

引用

页码：949 / 951

页数：3

共 40 条

[1] Unconventional acceptor and donor functional groups linked by a captodative spacer [J].

Alcalde, E ;

Gisbert, M ;

Pons, JM ;

PerezGarcia, L .

TETRAHEDRON, 1996, 52 (48) :15197-15208

[2] IDENTIFICATION OF 4(5)-IODOHISTIDINE AS PRODUCT OF LIMITED IODINATION OF HISTIDINE [J].

BENSUSAN, HB ;

NAIDU, MSR .

BIOCHEMISTRY, 1967, 6 (01) :12-&

[3] SYNTHESIS OF SOME POLYIMIDAZOLE LIGANDS RELATED TO ZINC ENZYMES [J].

BRESLOW, R ;

HUNT, JT ;

SMILEY, R ;

TARNOWSKI, T .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (16) :5337-5342

[4] SYNTHESIS AND PHYSICAL STUDIES OF PYRIDINE AND IMIDAZOLE CONTAINING TRIDENTATE METAL-BINDING LIGANDS [J].

BROWN, RS ;

HUGUET, J .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1980, 58 (09) :889-901

[5] THE SYNTHESIS OF TRIPODAL NITROGEN DONOR LIGANDS AND THEIR CHARACTERIZATION AS PD(II)ME2 AND PD(III)ME DERIVATIVES [J].

BYERS, PK ;

CANTY, AJ ;

HONEYMAN, RT .

JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1990, 385 (03) :417-427

[6] SYNTHESIS OF KETONES AND METHANOLS CONTAINING PYRIDINYL AND N-METHYLIMIDAZOLYL GROUPS [J].

CANTY, AJ ;

GEORGE, EE ;

LEE, CV .

AUSTRALIAN JOURNAL OF CHEMISTRY, 1983, 36 (02) :415-418

[7] SYNTHESIS AND CHARACTERIZATION OF COPPER(II) COMPLEXES OF NEW TRIPODAL POLYIMIDAZOLE LIGANDS [J].

CHEN, S ;

RICHARDSON, JF ;

BUCHANAN, RM .

INORGANIC CHEMISTRY, 1994, 33 (11) :2376-2382

[8]

CLIFF MD, 1994, SYNTHESIS-STUTTGART, P681

[9] Palladium catalysed coupling of imidazoles to alkynyl and vinyl substrates [J].

Cliff, MD ;

Pyne, SG .

TETRAHEDRON, 1996, 52 (43) :13703-13712

[10] A novel pentadentate ligand 2,6-bis[methoxybis(2-pyridyl)methyl]pyridine L for mononuclear iron(II) and manganese(II) compounds; Synthesis and crystal structures of [FeL(MeCN)][ClO4](2) and [(MnL(H2O)][ClO4](2) [J].

deVries, ME ;

LaCrois, RM ;

Roelfes, G ;

Kooijman, H ;

Spek, AL ;

Hage, R ;

Feringa, BL .

CHEMICAL COMMUNICATIONS, 1997, (16) :1549-1550

← 1 2 3 4 →