Live Long and Prosper for Antigen Cross-Presentation

被引：2
|
作者：
Muenz, Christian [1 ]
机构：
[1] Univ Zurich, Inst Expt Immunol, Viral Immunobiol, CH-8057 Zurich, Switzerland
来源：
IMMUNITY | 2015年 / 43卷 / 06期
关键词：
CROSSPRESENTATION; COMPARTMENT;
D O I：
10.1016/j.immuni.2015.11.013
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Even though proteolytic antigen fragments are displayed for cross-presentation, rapid proteolysis of endocytosed antigens inhibits this process. In this issue of Immunity, Alloatti et al. (2015) describe how maturing dendritic cells keep phagosomes and lysosomes apart to ensure extended antigen life that leads to prosperous cross-presentation.
引用
收藏
页码：1028 / +
页数：4
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