Radical fluorination powered expedient synthesis of 3-fluorobicyclo[1.1.1]pentan-1-amine

被引：22

作者：

Goh, Yi Ling ^{[1
]}

Adsool, Vikrant A. ^{[1
]}

机构：

[1] ASTAR, ICES, Singapore 138665, Singapore

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2015年 / 13卷 / 48期

关键词：

RING-SYSTEM; TRANSMISSION;

D O I：

10.1039/c5ob02066b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Exploration of novel chemical space, a modern trend in medicinal chemistry, is heavily reliant on synthetic access to new and interesting building blocks. In this direction, the following work describes an expedient synthesis of one such moiety, 3-fluorobicyclo[1.1.1]pentan-1-amine, by employing radical fluorination.

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收藏

页码：11597 / 11601

页数：5

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