Novel methods for liposome preparation

被引：418

作者：

Patil, Yogita P. ^{[1
]}

Jadhav, Sameer ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem Engn, Bombay 400076, Maharashtra, India

来源：

CHEMISTRY AND PHYSICS OF LIPIDS | 2014年 / 177卷

关键词：

Unilamellar; Multilamellar; Microfluidic; Electroformation; Supercritical fluid; GIANT UNILAMELLAR VESICLES; REVERSE-PHASE EVAPORATION; SINGLE BILAYER LIPOSOMES; FIELD-FLOW FRACTIONATION; SIZE-DISTRIBUTION; DRUG-DELIVERY; PHOSPHATIDYLCHOLINE VESICLES; PHYSICOCHEMICAL PROPERTIES; CRYOELECTRON MICROSCOPY; MICROFLUIDIC SYNTHESIS;

D O I：

10.1016/j.chemphyslip.2013.10.011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Liposomes are bilayer vesicles which have found use, among other applications, as drug delivery vehicles. Conventional techniques for liposome preparation and size reduction remain popular as these are simple to implement and do not require sophisticated equipment. However, issues related to scale-up for industrial production and scale-down for point-of-care applications have motivated improvements to conventional processes and have also led to the development of novel routes to liposome formation. In this article, these modified and new methods for liposome preparation have been reviewed and classified with the objective of updating the reader to recent developments in liposome production technology. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

引用

页码：8 / 18

页数：11

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