SEA BUCKTHORN PULP OIL TREATMENT CAN PREVENT METABOLIC SYNDROME IN HYPERTRIGLYCERIDEMIC WAIST FENOTYPE OBESE CHILDREN

The aim of this study was to determine the effects of Sea Buckthorn pulp oil intake (800 mg/day, 60 days) in hypertriglyceridemic waist phenotype obese children. Forty one obese children (10-18 years old) and thirty controls were involved. Modified ATP III (Adult Treatment Panel III) cut points for serum triglycerides (>= 110 mg/dL) and waist circumference (>= 90th percentile for age and sex) were used to divide obese children. Hypertriglyceridemic waist fenotype (n=17) and obese nonhypertriglyceridemic (n=24) obese groups were formed. Metabolic and inflammatory parameters were measured before and after sea buckthorn terapy. Metabolic syndrome was present in 14.25% obese children and all these subjects were from hypertriglyceridemic waist fenotype group. Comparing the obese groups, in hypertriglyceridemic waist fenotype obese children, the values for triglycerides (p<0.001), uric acid (p<0.004), C peptide (p<0.04), leptin (p<0.04), alanine aminotransferase (ALT) (p<0.05) and waist circumference (p<0.02), were increased, while high density lipoprotein-cholesterol (HDL-C) (p<0.01) was decreased. After treatment, triglycerides, blood pressure, leptin, C peptide and ceruloplasmin were decreased, while albumin was increased. In conclusion, in hypertriglyceridemic waist phenotype obese children, sea buckthorn pulp oil terapy (800mg/day, 60 days) prevents metabolic syndrome, by reducing triglyceridemia and blood pressure. Also, the treatment has a weak antiinflammatory effect.