Cleft lip and palate - risk factors, prenatal diagnosis, and health consequences

被引：0

作者：

Bilinska, Maria ^{[1
]}

Osmola, Krzysztof ^{[2
]}

机构：

[1] Klin & Katedra Chirurg Stomatol UM, Ul Bukowska 70, PL-60812 Poznan, Poland

[2] Katedra & Klin Chirurg Szczekowo Twarzowej UM, Poznan, Poland

来源：

GINEKOLOGIA POLSKA | 2015年 / 86卷 / 11期

关键词：

cleft lip; cleft palate; risk factors; prenatal diagnosis; MATERNAL ALCOHOL-CONSUMPTION; ORAL CLEFTS; OROFACIAL CLEFTS; ANTENATAL DIAGNOSIS; CIGARETTE-SMOKING; GENE VARIANTS; PREGNANCY; GENOTYPE; SUPPLEMENTATION; METABOLISM;

D O I：

暂无

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Cleft lip and/or palate is a diverse and important group of congenital malformations. The incidence is estimated at 1 in 600-1000 births worldwide. In Poland, there are 2-3 cases noted per 1000 live births. The process of the formation of a correctly developed lip and palate can be impaired by a variety of factors, including the extremely important role of the interaction between genetic and environmental factors (smoking, alcohol consumption, medication use, and exposure to certain chemicals). This study focuses on environmental risk factors, prenatal diagnosis, and health consequences of cleft lip and palate.

引用

页码：862 / 866

页数：5

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