Ghrelin: update on a novel hormonal system

被引:59
作者
Korbonits, M [1 ]
Grossman, AB [1 ]
机构
[1] Univ London St Bartholomews Hosp Med Coll, Dept Endocrinol, London EC1A 7BE, England
关键词
D O I
10.1530/eje.0.151S067
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Ghrelin is a peptide hormone secreted into the circulation from the stomach but also synthesised in a number of tissues, suggesting both endocrine and paracrine effects. These include: stimulation of GH, prolactin and ACTH secretion: an increase in appetite; a diabetogenic effect on carbohydrate metabolism; positive inotropic effects on heart; vasodilatation; and effects on cell proliferation. The possibility of chronic manipulation of the ghrelin system on body weight, growth and appetite remains an exciting new field of exploration.
引用
收藏
页码:S67 / S70
页数:4
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