Microfabrication of hydrogels for biomedical applications

被引：1

作者：

Yu, T ^{[1
]}

Chiellini, F ^{[1
]}

Schmaljohan, D ^{[1
]}

Solaro, R ^{[1
]}

Ober, C ^{[1
]}

机构：

[1] Cornell Univ, Ithaca, NY 14850 USA

来源：

ADVANCES IN RESIST TECHNOLOGY AND PROCESSING XIX, PTS 1 AND 2 | 2002年 / 4690卷

关键词：

photolithography; microfabrication; hydrogel; 2-hydroxyethyl methacrylate;

D O I：

10.1117/12.474288

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Hydrogels have gained general acceptance as biocompatible materials and are the basis of many promising applications in tissue engineering, drug release formulations and biosensors. Polymer processing techniques that can generate miniature hydrogel micro structures are not only critical as scaffolds for tissue re-growth but also very effective for increasing the efficiency of drug delivery and biosensors. Our approach is to use both optical and soft lithographic methods to microfabricate hydrogels. In this paper, we describe a photolithographic process to pattern hydrogel materials and analyze factors influencing sensitivity and lateral resolution. The model system we are investigating is based on 2-hydroxyethyl methacrylate (HEMA), which is well known for its non-toxicity and its widespread use in the contact lens industry.

引用

页码：854 / 860

页数：7

共 13 条

[1] pH-sensitive thin hydrogel microfabricated by photolithography [J].