Severe Bleeding and Perforation Are Rare Complications of Endoscopic Ultrasound-Guided Fine Needle Aspiration for Pancreatic Masses: An Analysis of 3,090 Patients from 212 Hospitals

被引：41

作者：

Hamada, Tsuyoshi ^{[1
]}

Yasunaga, Hideo ^{[2
]}

Nakai, Yousuke ^{[1
]}

Isayama, Hiroyuki ^{[1
]}

Horiguchi, Hiromasa ^{[3
]}

Matsuda, Shinya ^{[4
]}

Fushimi, Kiyohide ^{[5
]}

Koike, Kazuhiko ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Med, Dept Gastroenterol, Tokyo 1138655, Japan

[2] Univ Tokyo, Sch Publ Hlth, Dept Hlth Econ & Epidemiol Res, Tokyo 1138655, Japan

[3] Natl Hosp Org Headquarters, Clin Res Ctr, Dept Clin Data Management & Res, Tokyo, Japan

[4] Tokyo Med & Dent Univ, Dept Hlth Care Informat, Tokyo, Japan

[5] Univ Occupat & Environm Hlth, Dept Prevent Med & Community Hlth, Kitakyushu, Fukuoka 807, Japan

来源：

GUT AND LIVER | 2014年 / 8卷 / 02期

关键词：

Hemorrhage; Perforation; Endoscopic ultrasound-guided fine needle aspiration; Pancreas; DOSE ASPIRIN THERAPY; DIAGNOSIS; ULTRASONOGRAPHY; MORTALITY; CANCER; FNA;

D O I：

10.5009/gnl.2014.8.2.215

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background/Aims: Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is useful for the pathological diagnosis of pancreatic masses, but patients are susceptible to severe bleeding and perforation. Because the incidence and severity of these complications have not been fully evaluated. Methods: We aimed to evaluate severe bleeding and perforation after EUS-FNA for pancreatic masses using large-scale data derived from a Japanese nationwide administrative database. Results: In total, 3,090 consecutive patients from 212 low-to high-volume hospitals were analyzed. Severe bleeding requiring transfusion or endoscopic treatment occurred in seven patients (0.23%), and no perforation was observed. No patient mortality was recorded within 30 days of EUS-FNA. The rate of severe bleeding in low-volume hospitals was significantly higher than that in medium- and high-volume hospitals (0.48% vs 0.10%, p=0.045). Conclusions: Severe bleeding and perforation following EUS-FNA for pancreatic masses are rare, and the procedure is safe.

引用

页码：215 / 218

页数：4

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