The potential role of bacteria in pancreatic cancer: a systematic review

被引：20

作者：

Li, Ping ^{[1
]}

Shu, Yongqian ^{[1
]}

Gu, Yanhong ^{[1
]}

机构：

[1] Nanjing Med Univ, Dept Oncol, Affiliated Hosp 1, Nanjing 210029, Jiangsu, Peoples R China

来源：

CARCINOGENESIS | 2020年 / 41卷 / 04期

关键词：

HELICOBACTER-PYLORI INFECTION; ABO BLOOD-GROUP; PERIODONTAL-DISEASE; HEALTH-PROFESSIONALS; ORAL MICROBIOTA; GUT MICROBIOTA; RISK; ASSOCIATION; OBESITY; SEROPOSITIVITY;

D O I：

10.1093/carcin/bgaa013

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Pancreatic cancer is a lethal and devastating disease in the worldwide. Recognized risk factors for pancreatic cancer include cigarette smoking, obesity, type II diabetes and chronic pancreatitis. Other factors such as variant ABO blood type and Helicobacter pylori may also play an important role in pancreatic carcinogenesis. Recently, growing evidence suggests that the association between bacteria and pancreatic cancer is positive and related immune/inflammation activation and increased nitrosamine exposure may be its potential mechanism. Interestingly, it is debatable whether the relationship of bacteria and pancreatic cancer is causative, reactive or parallel and future studies are in progress. Here we review recent progress in pancreatic cancer and its related bacteria.

引用

页码：397 / 404

页数：8

共 79 条

[1] Defining the normal bacterial flora of the oral cavity [J].

Aas, JA ;

Paster, BJ ;

Stokes, LN ;

Olsen, I ;

Dewhirst, FE .

JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (11) :5721-5732

[2] Periodontal disease, Porphyromonas gingivalis serum antibody levels and orodigestive cancer mortality [J].

Ahn, Jiyoung ;

Segers, Stephanie ;

Hayes, Richard B. .

CARCINOGENESIS, 2012, 33 (05) :1055-1058

[3] Mechanisms of Obesity-Induced Gastrointestinal Neoplasia [J].

Aleman, Jose O. ;

Eusebi, Leonardo H. ;

Ricciardiello, Luigi ;

Patidar, Kavish ;

Sanyal, Arun J. ;

Holt, Peter R. .

GASTROENTEROLOGY, 2014, 146 (02) :357-373

[4]

[Anonymous], 2013, CANCER RES, DOI DOI 10.1158/1538-7445.AM2013-101

[5] An Exploration of Shared Genetic Risk Factors Between Periodontal Disease and Cancers: A Prospective Co-Twin Study [J].

Arora, Manish ;

Weuve, Jennifer ;

Fall, Katja ;

Pedersen, Nancy L. ;

Mucci, Lorelei A. .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 2010, 171 (02) :253-259

[6] The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL [J].

Aykut, Berk ;

Pushalkar, Smruti ;

Chen, Ruonan ;

Li, Qianhao ;

Abengozar, Raquel ;

Kim, Jacqueline I. ;

Shadaloey, Sorin A. ;

Wu, Dongling ;

Preiss, Pamela ;

Verma, Narendra ;

Guo, Yuqi ;

Saxena, Anjana ;

Vardhan, Mridula ;

Diskin, Brian ;

Wang, Wei ;

Leinwand, Joshua ;

Kurz, Emma ;

Rossi, Juan A. Kochen ;

Hundeyin, Mautin ;

Zambrinis, Constantinos ;

Li, Xin ;

Saxena, Deepak ;

Miller, George .

NATURE, 2019, 574 (7777) :264-+

[7] A meta-analysis of obesity and the risk of pancreatic cancer [J].

Berrington de Gonzalez, A ;

Sweetland, S ;

Spencer, E .

BRITISH JOURNAL OF CANCER, 2003, 89 (03) :519-523

[8] Oral Health and the Oral Microbiome in Pancreatic Cancer: An Overview of Epidemiological Studies [J].

Bracci, Paige M. .

CANCER JOURNAL, 2017, 23 (06) :310-314

[9] You are what you eat [J].

Bruessow, Harald ;

Parkinson, Scott J. .

NATURE BIOTECHNOLOGY, 2014, 32 (03) :243-245

[10] Investigating the Association Between Periodontal Disease and Risk of Pancreatic Cancer [J].

Chang, Jeffrey S. ;

Tsai, Chia-Rung ;

Chen, Li-Tzong ;

Shan, Yan-Shen .

PANCREAS, 2016, 45 (01) :134-141

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