Warfarin vs aspirin for symptomatic intracranial stenosis: Subgroup analyses from WASID

被引：134

作者：

Kasner, S. E.

Lynn, M. J.

Chimowitz, M. I.

Frankel, M. R.

Howlett-Smith, H.

Hertzberg, V. S.

Chaturvedi, S.

Levine, S. R.

Stern, B. J.

Benesch, C. G.

Jovin, T. G.

Sila, C. A.

Romano, J. G.

机构：

[1] Univ Penn, Dept Neurol, Med Ctr, Philadelphia, PA 19104 USA

[2] Emory Univ, Dept Biostat, Atlanta, GA 30322 USA

[3] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA

[4] Emory Univ, Sch Med, Dept Neurol, Atlanta, GA 30322 USA

[5] Wayne State Univ, Dept Neurol, Detroit, MI USA

[6] Mt Sinai Sch Med, Dept Neurol, New York, NY USA

[7] Univ Maryland, Dept Neurol, Baltimore, MD 21201 USA

[8] Univ Rochester, Sch Med, Dept Neurol, Rochester, NY USA

[9] Univ Pittsburgh, Sch Med, Dept Neurol, Pittsburgh, PA USA

[10] Cleveland Clin Fdn, Dept Neurol, Cleveland, OH 44195 USA

[11] Univ Miami, Sch Med, Dept Neurol, Miami, FL 33152 USA

来源：

NEUROLOGY | 2006年 / 67卷 / 07期

关键词：

D O I：

10.1212/01.wnl.0000238506.76873.2f

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The WASID trial showed no advantage of warfarin over aspirin for preventing the primary endpoint of ischemic stroke, brain hemorrhage, or vascular death. In analyses of selected subgroups, there was no definite benefit from warfarin. Warfarin reduced the risk of the primary endpoint among patients with basilar artery stenosis, but there was no reduction in stroke in the basilar artery territory or benefit for vertebral artery stenosis or posterior circulation disease in general.

引用

页码：1275 / 1278

页数：4

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