A Water-Soluble Copper(II) Complex for the Selective Fluorescence Detection of Nitric Oxide/Nitroxyl and Imaging in Living Cells

被引：32
|
作者：
Sun, Xiaolong [1 ]
Kim, Gyoungmi [2 ]
Xu, Yufang [3 ]
Yoon, Juyoung [2 ]
James, Tony D. [1 ]
机构：
[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England
[2] Ewha Womans Univ, Dept Chem & Nano Sci, Seoul 120750, South Korea
[3] E China Univ Sci & Technol, Sch Pharm, Meilong Rd 130, Shanghai 200237, Peoples R China
来源：
CHEMPLUSCHEM | 2016年 / 81卷 / 01期
基金：
新加坡国家研究基金会;
关键词：
cell imaging; copper; fluorescence probes; nitric oxide; nitroxyl; DEHYDROASCORBIC ACID; OXIDE PRODUCTION; AQUEOUS-SOLUTION; PROBE; 4,5-DIAMINOFLUORESCEIN; NITROXYL; SENSITIVITY; SYSTEM; NO;
D O I：
10.1002/cplu.201500436
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel water-soluble copper(II) naphthalimide complex fluorescent probe was devised and displayed significant fluorescence turn-on response for nitric oxide and nitroxyl over other biologically relevant reactive oxygen species under physiological conditions. The dual-analyte recognition of this simple and sensitive probe was successfully applied for the imaging of exogenous and endogenous NO and HNO in living cells.
引用
收藏
页码：30 / 34
页数：5
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