Neutrophils/Lymphocytes Ratio in Patients With Cardiac Syndrome X and Its Association With Carotid Intima-Media Thickness

被引：53

作者：

Demirkol, Sait ^{[1
]}

Balta, Sevket ^{[1
]}

Unlu, Murat ^{[2
]}

Arslan, Zekeriya ^{[3
]}

Cakar, Mustafa ^{[4
]}

Kucuk, Ugur ^{[1
]}

Celik, Turgay ^{[1
]}

Arslan, Erol ^{[4
]}

Turker, Turker ^{[5
]}

Iyisoy, Atila ^{[1
]}

Yokusoglu, Mehmet ^{[1
]}

机构：

[1] Gulhane Mil Med Acad, Sch Med, Dept Cardiol, TR-06018 Ankara, Turkey

[2] Beytepe Hosp, Dept Cardiol, Ankara, Turkey

[3] Gelibolu Hosp, Dept Cardiol, Canakkale, Turkey

[4] Gulhane Mil Med Acad, Sch Med, Dept Internal Med, TR-06018 Ankara, Turkey

[5] Gulhane Mil Med Acad, Sch Med, Dept Epidemiol, TR-06018 Ankara, Turkey

来源：

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS | 2014年 / 20卷 / 03期

关键词：

cardiac syndrome X; neutrophils and lymphocytes ratio; carotid intima-media thickness; LONG-TERM MORTALITY; NEUTROPHIL-LYMPHOCYTE RATIO; C-REACTIVE PROTEIN; NEUTROPHIL/LYMPHOCYTE RATIO; MYOCARDIAL-INFARCTION; ELEVATED NEUTROPHIL; CORONARY; PATHOPHYSIOLOGY; INFLAMMATION; DYSFUNCTION;

D O I：

10.1177/1076029612467227

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Neutrophils and lymphocytes (N/L) ratio and carotid intima-media thickness (C-IMT) value have been studied as new predictors of cardiovascular risk. We aimed to investigate N/L ratio and C-IMT value in patients with cardiac syndrome X (CSX) and compare patients with coronary artery disease (CAD) and normal participants. A total of 288 participants were enrolled in the study. The N/L ratio and C-IMT value were compared among the 3 groups. There were no statistically significant differences in N/L levels between CSX and CAD groups. The N/L ratio was found significantly increased in patients with CSX and CAD, compared to the control group. Patients with CAD and CSX had significantly higher C-IMT value compared to control participants. Significant positive correlation was found between C-IMT value and plasma level of N/L ratio. The relationship among CSX and higher N/L ratio level and C-IMT suggests that endothelial dysfunction may contribute to the etiopathogenesis of the CSX.

引用

页码：250 / 255

页数：6

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