Biological Activities of Some New Secondary Metabolites Isolated from Endophytic Fungi: A Review Study

被引:89
作者
Zheng, Ruihong [1 ]
Li, Shoujie [1 ]
Zhang, Xuan [1 ]
Zhao, Changqi [1 ]
机构
[1] Beijing Normal Univ, Coll Life Sci, Gene Engn & Biotechnol Beijing Key Lab, 19 XinjiekouWai Ave, Beijing 100875, Peoples R China
关键词
new secondary metabolites; endophytic fungi; structural feature; biological activity; A-D; BIOACTIVE METABOLITES; ENDOLICHENIC FUNGUS; DERIVATIVES; ASPERGILLUS; INHIBITORS; SP; LACTONE; SESQUITERPENOIDS; MODULATION;
D O I
10.3390/ijms22020959
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Secondary metabolites isolated from plant endophytic fungi have been getting more and more attention. Some secondary metabolites exhibit high biological activities, hence, they have potential to be used for promising lead compounds in drug discovery. In this review, a total of 134 journal articles (from 2017 to 2019) were reviewed and the chemical structures of 449 new metabolites, including polyketides, terpenoids, steroids and so on, were summarized. Besides, various biological activities and structure-activity relationship of some compounds were aslo described.
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页码:1 / 75
页数:80
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