Refractive index of adipose tissue and lipid droplet measured in wide spectral and temperature ranges

被引:37
作者
Yanina, Irina Yu [1 ,2 ]
Lazareva, Ekaterina N. [1 ,2 ,3 ]
Tuchin, Valery V. [1 ,2 ,4 ]
机构
[1] Saratov NG Chernyshevskii State Univ, Natl Res Univ, Res Educ Inst Opt & Biophoton, 83 Astrakhanskaya Str, Saratov 410012, Russia
[2] Tomsk State Univ, Natl Res Univ, Interdisciplinary Lab Biophoton, 36 Lenin Av, Tomsk 634050, Russia
[3] Immanuel Kant Balt Fed Univ, Ctr Functionalized Magnet Mat FunMagMa, Kaliningrad 236041, Russia
[4] Russian Acad Sci, Precis Mech & Control Inst, Lab Laser Diagnost Tech & Living Syst, 24 Rabochaya, Saratov 410028, Russia
基金
俄罗斯基础研究基金会;
关键词
OPTICAL-PROPERTIES; FRACTIONAL PHOTOTHERMOLYSIS; BIOLOGICAL TISSUES; PHASE-TRANSITIONS; LASER; LIGHT; WATER; TRANSMISSION; REFLECTION; MEMBRANE;
D O I
10.1364/AO.57.004839
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
This study presents refractive index measurements of human and porcine adipose tissues and lipid droplet content in the visible and near-infrared. The coefficients of the Sellmeier formula were calculated for approximation of tissue dispersion. For the first time, to the best of our knowledge, the phase transition temperatures and temperature increments dn/dT of adipose tissue were quantified for a wide wavelength range from 480 to 1550 nm and from room temperature up to 50(degrees)C. For human abdominal adipose tissue, the refractive index increment averaged across all wavelengths is dn/dT = -(3.54 +/- 0.15) x 10(-4 degrees)C(-1), for porcine tissue dn/dT = -7.92(0.74) x 10(_4 degrees)C(-1), and for porcine lipid droplet dn/dT = -6.01(0.29) x 10(-4 degrees)C(-1). Data available in literature for refractive indices of adipose tissues measured by different techniques are summarized and compared with the received data. (C) 2018 Optical Society of America
引用
收藏
页码:4839 / 4848
页数:10
相关论文
共 88 条
[11]  
Bolin FP, 1989, APPL OPTICS, V28, P2297
[12]  
Caprita R., 2014, Scientific Papers: Animal Science and Biotechnologies, V47, P158
[13]   Simple multimodal optical technique for evaluation of free/bound water and dispersion of human liver tissue [J].
Carneiro, Ise ;
Carvalho, Sonia ;
Henrique, Rui ;
Oliveira, Luis ;
Tuchin, Valery V. .
JOURNAL OF BIOMEDICAL OPTICS, 2017, 22 (12)
[14]  
Castro G. S. F., 2012, REV NUTR, V45, P56
[15]   Measurement of the refractive index of biotissue at four laser wavelengths [J].
Cheng, SY ;
Shen, HY ;
Zhang, G ;
Huang, CH ;
Huang, XJ .
OPTICS IN HEALTH CARE AND BIOMEDICAL OPTICS: DIAGNOSTICS AND TREATMENT, 2002, 4916 :172-176
[16]  
Cherkasova OA, 2007, BIOFIZIKA+, V52, P687
[17]   Refractometer assessment of colostral and serum IgG and milk total solids concentrations in dairy cattle [J].
Chigerwe, Munashe ;
Hagey, Jill V. .
BMC VETERINARY RESEARCH, 2014, 10
[18]   Temperature-dependent optical properties of Intralipid® measured with frequency-domain photon-migration spectroscopy [J].
Cletus, Biju ;
Kuennemeyer, Rainer ;
Martinsen, Paul ;
McGlone, Vincent Andrew .
JOURNAL OF BIOMEDICAL OPTICS, 2010, 15 (01)
[19]   Refractive index measurement of turbid media by transmission of backscattered light near the critical angle [J].
Contreras-Tello, H. ;
Garcia-Valenzuela, A. .
APPLIED OPTICS, 2014, 53 (21) :4768-4778
[20]   Understanding the performance of Abbe-type refractometers with optically absorbing fluids [J].
Contreras-Tello, H. ;
Marquez-Islas, R. ;
Vazquez-Estrada, O. ;
Sanchez-Perez, C. ;
Garcia-Valenzuela, A. .
MEASUREMENT SCIENCE AND TECHNOLOGY, 2014, 25 (07)