Effect of Probiotics on Intestinal Barrier Function

被引：99
|
作者：
Mennigen, Rudolf [1 ]
Bruewer, Matthias [1 ]
机构：
[1] Univ Hosp Muenster, Dept Gen & Visceral Surg, D-48149 Munster, Germany
来源：
MOLECULAR STRUCTURE AND FUNCTION OF THE TIGHT JUNCTION: FROM BASIC MECHANISMS TO CLINICAL MANIFESTATIONS | 2009年 / 1165卷
关键词：
probiotics; inflammatory bowel disease; epithelial barrier; intestinal barrier; tight junction; bacterial translocation; INFLAMMATORY-BOWEL-DISEASE; PLACEBO-CONTROLLED TRIAL; BACTERIAL-INFECTION RATES; RANDOMIZED CLINICAL-TRIAL; SEVERE ACUTE-PANCREATITIS; ACTIVE CROHNS-DISEASE; DOUBLE-BLIND TRIAL; EPITHELIAL BARRIER; ESCHERICHIA-COLI; ULCERATIVE-COLITIS;
D O I：
10.1111/j.1749-6632.2009.04059.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Impairment of the intestinal barrier is a key event in various gastrointestinal diseases, including inflammatory bowel diseases, celiac disease, gastrointestinal infections, diarrhea, and critical illness. Recent studies demonstrated that probiotic bacteria have beneficial effects in these diseases by effectively improving intestinal barrier function. This article reviews available data on the effect of probiotics on intestinal barrier function in vitro, in animal models, and in clinical studies.
引用
收藏
页码：183 / 189
页数：7
相关论文
共 50 条
  • [1] Rotavirus, Intestinal Barrier Function, and Probiotics
    Lowe, Mark E.
    JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2013, 57 (06): : 687 - 687
  • [2] Prebiotics and Probiotics Maintain the Intestinal Barrier Function
    Ducray, Henri Alexandre Giblot
    Globa, Ludmila
    Pustovyy, Oleg
    Vodyanoy, Vitaly
    Sorokulova, Iryna
    FASEB JOURNAL, 2019, 33
  • [3] Protective effect of probiotics on intestinal barrier function in malnourished rats after liver transplantation
    Ren, Zhi-Gang
    Liu, Hui
    Jiang, Jian-Wen
    Jiang, Li
    Chen, Hui
    Xie, Hai-Yang
    Zhou, Lin
    Zheng, Shu-Sen
    HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL, 2011, 10 (05) : 489 - 496
  • [4] Protective effect of probiotics on intestinal barrier function in malnourished rats after liver transplantation
    Zhi-Gang Ren
    and Institute of Immunology
    Hepatobiliary&PancreaticDiseasesInternational, 2011, 10 (05) : 489 - 496
  • [5] Recent Progress in Understanding the Involvement of miRNA in the Protective Effect of Probiotics on Intestinal Barrier Function
    Li A.
    Zhang X.
    Li Y.
    Yang J.
    Ma X.
    Jia X.
    Du P.
    Shipin Kexue/Food Science, 2020, 41 (19): : 318 - 326
  • [6] The Effect of Bacterial Infections, Probiotics and Zonulin on Intestinal Barrier Integrity
    Serek, Pawel
    Oleksy-Wawrzyniak, Monika
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (21)
  • [7] Can probiotics modulate human disease by impacting intestinal barrier function?
    Bron, Peter A.
    Kleerebezem, Michiel
    Brummer, Robert-Jan
    Cani, Patrice D.
    Mercenier, Annick
    MacDonald, Thomas T.
    Garcia-Rodenas, Clara L.
    Wells, Jerry M.
    BRITISH JOURNAL OF NUTRITION, 2017, 117 (01) : 93 - 107
  • [8] Intestinal Epithelial Barrier Regulation with Probiotics
    Paveljsek, Diana
    Jerala, Roman
    Rogelj, Irena
    JOURNAL OF CLINICAL GASTROENTEROLOGY, 2020, 54 : S19 - S19
  • [9] How do intestinal probiotics restore the intestinal barrier?
    Gou, Hong-Zhong
    Zhang, Yu-Lin
    Ren, Long-Fei
    Li, Zhen-Jiao
    Zhang, Lei
    FRONTIERS IN MICROBIOLOGY, 2022, 13
  • [10] Effects of compound probiotics on intestinal barrier function and caecum microbiota composition of broilers
    Wu, Yunhui
    Yang, Fan
    Jiang, Wenjuan
    Hu, Aiming
    Xiong, Zhiwei
    Yang, Shuqiu
    Cao, Panpan
    Cao, Zhanyou
    Xiong, Zhonghua
    Cao, Huabin
    AVIAN PATHOLOGY, 2022, 51 (05) : 465 - 475
12345