Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

被引：68

作者：

Postma, TJ

Klein, M

Verstappen, CCP

Bromberg, JEC

Swennen, M

Langendijk, JA

Taphoorn, MJB

Scheltens, P

Slotman, BJ

van der Ploeg, HM

Aaronson, NK

Heimans, JJ

机构：

[1] Vrije Univ Amsterdam, Med Ctr, Dept Neurol, NL-1007 MB Amsterdam, Netherlands

[2] Vrije Univ Amsterdam, Med Ctr, Dept Psychol Med, NL-1007 MB Amsterdam, Netherlands

[3] Vrije Univ Amsterdam, Med Ctr, Dept Radiat Oncol, NL-1007 MB Amsterdam, Netherlands

[4] Univ Amsterdam, Med Ctr, Dept Neurol, Amsterdam, Netherlands

[5] Netherlands Canc Inst, Dept Psychosocial Res & Epidemiol, Amsterdam, Netherlands

来源：

NEUROLOGY | 2002年 / 59卷 / 01期

关键词：

D O I：

10.1212/WNL.59.1.121

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.

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页码：121 / 123

页数：3

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