Dissolved oxygen concentration-controlled feeding of substrate into Kluyveromyces fragilis culture

被引：11

作者：

Barberis, SE

Segovia, RF

机构：

[1] Laboratorio de Microbiología Industrial, Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis

[2] Bromatología, Universidad Nacional de San Luis

来源：

BIOTECHNOLOGY TECHNIQUES | 1997年 / 11卷 / 11期

关键词：

D O I：

10.1023/A:1018421123983

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

beta-Galactosidase production by Kluyveromyces fragilis was optimized by controling dissolved oxygen concentration (DOG) due to the enzyme production rate being strongly dependent on this parameter in the broth. A system of automatic control of substrate inflow which depends on DOC has been devised. This strategy has resulted in a significant and reproducible improvement in the performance of the fermentation. Volumetric enzyme production rates were greater in this system than in batch culture of the microorganism with DOC control.

引用

页码：797 / 799

页数：3

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