Impact of concomitant intrauterine adhesions on pregnancy outcomes and obstetric complications in women with a septate uterus

被引：1

作者：

Shen, Minghong ^{[1
,2
]}

Duan, Hua ^{[1
]}

Chang, Yanan ^{[1
]}

Lin, Qi ^{[1
]}

Chen, Chao ^{[1
]}

Wang, Sirui ^{[1
]}

机构：

[1] Capital Med Univ, Dept Minimally Invas Gynecol Ctr, Beijing Maternal & Child Hlth Care Hosp, Beijing Obstet & Gynecol Hosp, Beijing, Peoples R China

[2] Fujian Med Univ, Fujian Prov Hosp, Dept Gynecol, Shengli Clin Med Coll, Fuzhou, Fujian, Peoples R China

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 2022年 / 159卷 / 03期

关键词：

Asherman syndrome; intrauterine adhesions; obstetric outcome; pregnancy outcome; septate uterus; CONGENITAL UTERINE ANOMALIES; HYSTEROSCOPIC MANAGEMENT; REPRODUCTIVE OUTCOMES; ASHERMAN-SYNDROME; PREVALENCE;

D O I：

10.1002/ijgo.14260

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective To explore the impact of concomitant intrauterine adhesions (IUAs) on pregnancy outcomes and obstetric complications in women with a septate uterus. Methods This retrospective cohort included women with a septate uterus, with or without IUAs, between 2015 and 2019 in our hospital. The main outcomes were clinical pregnancy rate, live-birth rate, and obstetric complications. Results A total of 336 women with a septate uterus-105 women (31.3%) with IUAs and 231 (68.7%) women without IUAs-were analyzed. The rates of clinical pregnancy and live birth among women with moderate-to-severe IUAs were significantly decreased compared with those among women without IUAs (69.9% vs. 76.6%, odds ratio [OR] 0.51; 95% confidence interval [CI] 0.27-0.99, P = 0.046, and 57.0% vs. 67.1%, OR 0.53; 95% CI 0.30-0.95, P = 0.032, respectively). However, these rates were similar between women with mild IUAs and women without IUAs. Women with moderate-to-severe IUAs had a higher incidence of abnormal placentation than women with a septum only (13.2% vs. 1.3%, P = 0.001). Conclusion Concomitant moderate-to-severe IUAs significantly reduce the rates of clinical pregnancy and live birth and increase the risk of abnormal placentation in subsequent pregnancies in women with a septate uterus.

引用

页码：875 / 881

页数：7

共 22 条

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