Delayed-Onset Movement Disorder and Encephalopathy After Oxycodone Ingestion

被引:4
作者
Beatty, Christopher W. [1 ]
Ko, Ping-Ru [1 ]
Nixon, Jason [1 ]
Gospe, Sidney M., Jr. [1 ]
机构
[1] Univ Washington, Dept Neurol, Seattle, WA 98195 USA
关键词
MR SPECTROSCOPY; LEUKOENCEPHALOPATHY; BRAIN; RECEPTORS; METHADONE; TOXICITY; DRAGON;
D O I
10.1016/j.spen.2014.06.009
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We present the case of a 14-year-old girl with a biphasic course after oxycodone ingestion. Clinically, she had a rapid return to baseline after initial ingestion and presented a week later with new-onset ballism, akathisia, and encephalopathy. Neuroimaging" demonstrated bilateral globi pallidi and cerebellar lesions with a relative decrease of metabolite peaks on magnetic resonance spectroscopy. Her movement disorder was treated successfully with valproic acid and clonidine. Her cognitive functioning returned to baseline 3 months after ingestion. (C) 2014 Elsevier Inc. All rights reserved.
引用
收藏
页码:160 / 165
页数:6
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