Antiphospholipid antibodies and in vitro fertilization success: a meta-analysis

被引：96

作者：

Hornstein, MD

Davis, OK

Massey, JB

Paulson, RJ

Collins, JA

机构：

[1] Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Obstet & Gynecol, Boston, MA 02115 USA

[2] Cornell Univ, Weill Coll Med, Dept Obstet & Gynecol, Ithaca, NY USA

[3] Reprod Biol Associates, Atlanta, GA USA

[4] Univ So Calif, Sch Med, Dept Obstet & Gynecol, Los Angeles, CA 90033 USA

[5] McMaster Univ, Dept Obstet & Gynecol, Hamilton, ON, Canada

来源：

FERTILITY AND STERILITY | 2000年 / 73卷 / 02期

关键词：

antiphospholipid antibodies; in vitro fertilization; meta-analysis;

D O I：

10.1016/S0015-0282(99)00498-7

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: To evaluate whether the presence of antiphospholipid antibodies among women undergoing IVF affects the likelihood of IVF success. Design: A meta-analysis of seven eligible studies on antiphospholipid antibodies and IVF outcome. Main Outcome Measure(s): Odds ratios (ORs) and 95% confidence intervals (CIs) of an association between the presence of antiphospholipid antibodies and both clinical pregnancy and live birth from IVF. Result(s): There was no significant association between antiphospholipid abnormalities and either clinical pregnancy (OR 0.99: 95% CI 0.64-1.53) or live birth (OR 1.07; 95% CI 0.66-1.75) in IVF patients. Conclusion(s): The measurement of antiphospholipid antibodies is not warranted in patients undergoing IVF. (Fertil Steril(R) 2000;73:330-3. (C)2000 by American Society for Reproductive Medicine.).

引用

页码：330 / 333

页数：4

共 22 条

[1]

Balasch J, 1996, HUM REPROD, V11, P2310

[2] Intravenous immunoglobulin preceding in vitro fertilization-embryo transfer for patients with repeated failure of embryo transfer [J].