Copper-catalyzed domino synthesis of benzo[b]thiophene/imidazo[1,2-a]pyridines by sequential Ullmann-type coupling and intramolecular C(sp2)-H thiolation

被引：36
|
作者：
Yan, Kelu [1 ]
Yang, Daoshan [1 ]
Wei, Wei [1 ]
Lu, Shenglei [1 ]
Li, Guoqing [1 ]
Zhao, Caixia [1 ]
Zhang, Qingyun [1 ]
Wang, Hua [1 ]
机构：
[1] Qufu Normal Univ, Sch Chem & Chem Engn, Key Lab Pharmaceut Intermediates & Anal Nat Med, Qufu 273165, Shandong, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2016年 / 3卷 / 01期
基金：
中国国家自然科学基金;
关键词：
C-H BOND; ONE-POT SYNTHESIS; SUBSTITUTED BENZOTHIAZOLES; S-ALKENYLATION; ARYL HALIDES; EFFICIENT; SULFUR; THIOLS; FUNCTIONALIZATION; SULFENYLATION;
D O I：
10.1039/c5qo00311c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The copper-catalyzed double C-S bond formation via Ullmann-type S-arylation and C-H thiolation using K2S as a sulfur source is described. This novel one-step sulfur-incorporation method provides a straightforward avenue to benzo[b]thiophene and imidazo[1,2-a]pyridine frameworks.
引用
收藏
页码：66 / 70
页数：5
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