An ESIPT-Based Fluorescent Probe for Hydrazine Detection in Aqueous Solution and its Application in Living Cells

被引：39

作者：

Ju, Zhiyu ^{[1
]}

Li, Dapeng ^{[1
]}

Zhang, Di ^{[2
]}

Li, Dandan ^{[1
]}

Wu, Changzeng ^{[1
]}

Xu, Zhihong ^{[1
]}

机构：

[1] Xuchang Univ, Coll Chem & Chem Engn, Xuchang 461000, Peoples R China

[2] Henan Acad Agr Sci, Inst Qual Stand & Testing Technol Agroprod, Zhengzhou 450002, Peoples R China

来源：

JOURNAL OF FLUORESCENCE | 2017年 / 27卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Excited state intramolecular proton transfer; Fluorescence; Hydrazine; Biological imaging; PROTON-TRANSFER ESIPT; IN-VIVO; SELECTIVE DEPROTECTION; SOLID-STATE; GAS STATE; CHEMODOSIMETER; SENSOR; CHEMOSENSOR; CYSTEINE; CR3+;

D O I：

10.1007/s10895-016-1997-7

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A new fluorescent probe based on "protection-deprotection" sequence and the excited-state intramolecular proton transfer (ESIPT) effect was designed and synthesized. The probe responds rapidly and high selectively toward hydrazine at room temperature, and exhibits a low detection limit of 0.016 mu M (0.512 ppb), which is well below the safety level (10 ppb) as regulated by EPA. Moreover, it can be applied for the imaging of hydrazine in living cells.

引用

页码：679 / 687

页数：9

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