CHEMICAL COMPOSITION AND BIOLOGICAL ACTIVITY OF OIL PROPOLIS EXTRACT: AN ALTERNATIVE TO ETHANOLIC EXTRACT

被引：61

作者：

Buriol, Lilian ^{[1
]}

Finger, Daiane ^{[1
]}

Schmidt, Eduardo Morgado ^{[1
]}

dos Santos, Julio M. T. ^{[1
]}

da Rosa, Marcos Roberto ^{[1
]}

Quinaia, Sueli Percio ^{[1
]}

Torres, Yohandra Reyes ^{[1
]}

Dalla Santa, Herta Stutz ^{[2
]}

Pessoa, Claudia ^{[3
]}

de Moraes, Manoel Odorico ^{[3
]}

Costa-Lotufo, Leticia Veras ^{[3
]}

Pinheiro Ferreira, Paulo Michel ^{[3
]}

Helena Frankland Sawaya, Alexandra Christine ^{[4
]}

Eberlin, Marcos Nogueira ^{[4
]}

机构：

[1] Univ Estadual Centro Oeste, Dept Quim, Ctr Desenvolvimento Educac & Tecnol Guarapuava, BR-85040080 Guarapuava, PR, Brazil

[2] Univ Estadual Centro Oeste, Dept Engn Alimentos, Ctr Desenvolvimento Educac & Tecnol Guarapuava, BR-85040080 Guarapuava, PR, Brazil

[3] Univ Fed Ceara, Dept Fisiol & Farmacol, BR-60431970 Fortaleza, CE, Brazil

[4] Univ Estadual Campinas, Inst Quim, Campinas, SP, Brazil

来源：

QUIMICA NOVA | 2009年 / 32卷 / 02期

关键词：

oil propolis extract; phenolic compounds; antibacterial and cytotoxic activities; IONIZATION MASS-SPECTROMETRY; BRAZILIAN PROPOLIS; ANTIBACTERIAL ACTIVITY; IDENTIFICATION; CONSTITUENTS; ORIGIN; PLANTS;

D O I：

10.1590/S0100-40422009000200006

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Propolis is mostly used as hydroalcoholic extract. Recently there has been a growing number of patents dealing with new solvents for preparing propolis extracts. This study aimed to prepare edible oil propolis extracts and compare their chemical composition and biological activity with ethanolic propolis extracts. ESI-MS and spectrophotometric methods were used for qualitative and quantitative analyses, respectively. Antibacterial activity was evaluated by diffusion in agar. Cytotoxicity was tested by MTT assay using tumor cell lines. The oil is able to extract bioactive compounds from propolis. Further studies are needed to improve extraction efficiency and to characterize the active components.

引用

页码：296 / 302

页数：7

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