Laccase and Laccase-Mediated Systems in the Synthesis of Organic Compounds

被引：216

作者：

Mogharabi, Mehdi ^{[1
]}

Faramarzi, Mohammad Ali ^{[1
]}

机构：

[1] Univ Tehran Med Sci, Fac Pharm & Biotechnol, Dept Pharmaceut Biotechnol, Res Ctr, Tehran 14176, Iran

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2014年 / 356卷 / 05期

关键词：

biocatalysis; chemical mediators; laccase; organic synthesis; oxidation; ONE-POT SYNTHESIS; ENZYMATIC OXIDATIVE POLYMERIZATION; ASCOMYCETE PODOSPORA-ANSERINA; SOIL-ISOLATED ASCOMYCETE; REACTIVE TEXTILE DYES; EXTRACELLULAR LACCASE; TRAMETES-VERSICOLOR; FUNGAL LACCASES; BIOCHEMICAL-CHARACTERIZATION; IONIC LIQUIDS;

D O I：

10.1002/adsc.201300960

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Laccase, a blue multicopper oxidase, has recently received considerable attention because of its usefulness in oxidizing phenolic and non-phenolic compounds, as well as its suitability for organic synthesis, environmental pollutant treatment, and other biotechnological applications. This review covers recent studies on the structural properties, occurrence, reaction mechnisms, redox mediators of laccases and their application in organic synthesis procedures, such as dimerization, polymerization, oxidation, and amination. We also present a brief discussion on laccase activity in non-aqueous media. Given that the development of green protocols for the synthesis of pure compounds is one of the main goals of sustainable chemistry, the exploitation of laccases is expected to remain one of the most popular directions in future biocatalysis research.

引用

页码：897 / 927

页数：31

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