MAGNETIC RESONANCE IMAGING PATTERN RECOGNITION IN SPORADIC INCLUSION-BODY MYOSITIS

被引：94
作者：
Tasca, Giorgio [1 ]
Monforte, Mauro [2 ]
De Fino, Chiara [2 ]
Kley, Rudolf A. [3 ]
Ricci, Enzo [2 ]
Mirabella, Massimiliano [2 ]
机构：
[1] Don Carlo Gnocchi ONLUS Fdn, Milan, Italy
[2] Univ Cattolica Sacro Cuore, Sch Med, Inst Neurol, I-00168 Rome, Italy
[3] Ruhr Univ Bochum, Dept Neurol, Univ Hosp Bergmannsheil, Bochum, Germany
来源：
MUSCLE & NERVE | 2015年 / 52卷 / 06期
关键词：
MUSCULAR-DYSTROPHY; SKELETAL-MUSCLES; DIAGNOSIS; MYOPATHIES; MRI;
D O I：
10.1002/mus.24661
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Introduction: In sporadic inclusion-body myositis (IBM), additional tools are needed to confirm the diagnosis, particularly in clinically atypical or pathologically unproven patients. The aims of this study were to define the pattern of muscle MRI in IBM and to assess its accuracy in differentiating IBM from other myopathies that overlap with it clinically or pathologically. Methods: Blind assessment was done on the scans of 17 definite IBM, 2 possible IBM, and 118 patients with other myopathies. Results: The diagnostic accuracy to detect definite IBM was 95% for the typical pattern (with 100% specificity) and 97% for both typical and consistent patterns (with 97% specificity). Conclusions: Muscle MRI is an accurate tool for diagnostic work-up of suspected IBM patients and may be particularly helpful in patients with early disease or who lack the classical IBM pathology.
引用
收藏
页码：956 / 962
页数：7
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