Hypoglycemic activity of Bauhinia candicans in diabetic induced rabbits

被引：38

作者：

Fuentes, O

Arancibia-Avila, P

Alarcón, J

机构：

[1] Univ Bio Bio, Fac Ciencias, Lab Fisiol, Chillan, Chile

[2] Univ Bio Bio, Fac Ciencias, Dept Ciencias Basicas, Chillan, Chile

来源：

FITOTERAPIA | 2004年 / 75卷 / 06期

关键词：

Bauhinia candicans; hypoglycemic activity; diabetes;

D O I：

10.1016/j.fitote.2004.03.013

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The effect of different fractions of methanolic extract of Bauhinia candicans leaves were investigated on experimentally-induced diabetic rabbits. The crude extracts (8 mg/kg) showed hypoglycemic activity along with a reduced urinary glucose excretion. Among the fractions, the highest activity was exhibited by the butanolic fraction (fraction III). Moreover, fraction III reduced plasma glucose level also in normal, as well as, glucose loaded rabbits. These results suggest that B. candicans increases the peripheral metabolism of glucose. (C) 2004 Published by Elsevier B.V.

引用

页码：527 / 532

页数：6

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