Dysphagia and respiratory complications are the major problems in patients suffering from malignant strictures of the cervical esophagus. In inoperable cases, interventional palliation is the cornerstone of treatment. The aim of this study was to evaluate the use of self-expanding plastic stents (SEPS) in this group of patients. In a retrospective study, 23 patients suffering from various malignant obstructive diseases of the cervical esophagus, including squamous cell carcinoma (n = 10), laryngeal cancer (n = 7), lung cancer with esophageal invasion (n = 5), and metastatic breast cancer (n = 1), underwent SEPS placement, under endoscopic and fluoroscopic guidance. Tracheoesophageal fistula was documented in five patients. Technical success rate, improvement of dysphagia grade, and stent-related complications were evaluated after stent placement. Stent insertion was successfully achieved in all cases, namely in 20 patients at the first stent placement attempt and in three patients after a second attempt. Dysphagia grade was notably improved after 24 h. In two cases, major complications occurred. These were successfully treated without the need of stent extraction. Barium swallowing studies demonstrated complete sealing of all fistulas. Foreign-body sensation that gradually disappeared within the first week after stent placement was observed in eight patients. Recurrence of dysphagia occurred in three patients, due to hyperplastic tissue proliferation (n = 2) and tumor overgrowth (n = 1). Late migration of the stent was detected in one case after 67 days. SEPS placement is an effective and safe palliative treatment for malignant strictures of the cervical esophagus. Main advantages include easy retrievability and reduced rates of reinterventions.
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IRCCS Ist Clin Humanitas, Dept Gastroenterol, Digest Endoscopy Unit, I-20089 Milan, ItalyIRCCS Ist Clin Humanitas, Dept Gastroenterol, Digest Endoscopy Unit, I-20089 Milan, Italy
Repici, A.
Hassan, C.
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Nuovo Regina Margherita Hosp, Rome, ItalyIRCCS Ist Clin Humanitas, Dept Gastroenterol, Digest Endoscopy Unit, I-20089 Milan, Italy
Hassan, C.
Sharma, P.
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Univ Kansas, Sch Med, Kansas City, MO USA
Vet Affairs Med Ctr, Div Gastroenterol & Hepatol, Kansas City, MO USAIRCCS Ist Clin Humanitas, Dept Gastroenterol, Digest Endoscopy Unit, I-20089 Milan, Italy
Sharma, P.
Conio, M.
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IST, Gastroenterol Unit, Genoa, ItalyIRCCS Ist Clin Humanitas, Dept Gastroenterol, Digest Endoscopy Unit, I-20089 Milan, Italy
Conio, M.
Siersema, P.
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Univ Med Ctr Utrecht, Dept Gastroenterol & Hepatol, Utrecht, NetherlandsIRCCS Ist Clin Humanitas, Dept Gastroenterol, Digest Endoscopy Unit, I-20089 Milan, Italy
机构:
Gen Hosp, Dept Gastroenterol, C So Garibaldi 187-3, I-18038 San Remo, ItalyGen Hosp, Dept Gastroenterol, C So Garibaldi 187-3, I-18038 San Remo, Italy
Conio, Massimo
Blanchi, Sabrina
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Gen Hosp, Dept Gastroenterol, C So Garibaldi 187-3, I-18038 San Remo, ItalyGen Hosp, Dept Gastroenterol, C So Garibaldi 187-3, I-18038 San Remo, Italy
Blanchi, Sabrina
Filiberti, Rosangela
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Natl Inst Canc Res, Mol Epidemiol, Genoa, ItalyGen Hosp, Dept Gastroenterol, C So Garibaldi 187-3, I-18038 San Remo, Italy