Clinician judgment vs formal scales for predicting intracerebral hemorrhage outcomes

被引:85
作者
Hwang, David Y. [1 ]
Dell, Cameron A. [2 ]
Sparks, Mary J. [2 ]
Watson, Tiffany D. [2 ]
Langefeld, Carl D. [3 ,4 ]
Comeau, Mary E. [3 ,4 ]
Rosand, Jonathan [5 ]
Battey, Thomas W. K. [5 ]
Koch, Sebastian [6 ]
Perez, Mario L. [6 ]
James, Michael L. [7 ]
McFarlin, Jessica [7 ]
Osborne, Jennifer L. [8 ]
Woo, Daniel [8 ]
Kittner, Steven J. [9 ,10 ]
Sheth, Kevin N. [1 ]
机构
[1] Yale Univ, Sch Med, Dept Neurol, Div Neurocrit Care & Emergency Neurol, New Haven, CT 06510 USA
[2] Maryland Stroke Ctr, Baltimore, MD USA
[3] Wake Forest Sch Med, Ctr Publ Hlth Genom, Winston Salem, NC USA
[4] Wake Forest Sch Med, Dept Biostat Sci, Div Publ Hlth Sci, Winston Salem, NC USA
[5] Ctr Human Genet Res, Boston, MA USA
[6] Univ Miami, Miller Sch Med, Coral Gables, FL 33124 USA
[7] Duke Univ, Med Ctr, Durham, NC USA
[8] Univ Cincinnati, Coll Med, Dept Neurol, Cincinnati, OH 45221 USA
[9] Baltimore Vet Adm Med Ctr, Baltimore, MD USA
[10] Univ Maryland, Sch Med, Baltimore, MD USA
关键词
GRADING SCALE; MORTALITY; SCORE; VALIDATION; ACCURACY;
D O I
10.1212/WNL.0000000000002266
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective:To compare the performance of formal prognostic instruments vs subjective clinical judgment with regards to predicting functional outcome in patients with spontaneous intracerebral hemorrhage (ICH).Methods:This prospective observational study enrolled 121 ICH patients hospitalized at 5 US tertiary care centers. Within 24 hours of each patient's admission to the hospital, one physician and one nurse on each patient's clinical team were each asked to predict the patient's modified Rankin Scale (mRS) score at 3 months and to indicate whether he or she would recommend comfort measures. The admission ICH score and FUNC score, 2 prognostic scales selected for their common use in neurologic practice, were calculated for each patient. Spearman rank correlation coefficients (r) with respect to patients' actual 3-month mRS for the physician and nursing predictions were compared against the same correlation coefficients for the ICH score and FUNC score.Results:The absolute value of the correlation coefficient for physician predictions with respect to actual outcome (0.75) was higher than that of either the ICH score (0.62, p = 0.057) or the FUNC score (0.56, p = 0.01). The nursing predictions of outcome (r = 0.72) also trended towards an accuracy advantage over the ICH score (p = 0.09) and FUNC score (p = 0.03). In an analysis that excluded patients for whom comfort care was recommended, the 65 available attending physician predictions retained greater accuracy (r = 0.73) than either the ICH score (r = 0.50, p = 0.02) or the FUNC score (r = 0.42, p = 0.004).Conclusions:Early subjective clinical judgment of physicians correlates more closely with 3-month outcome after ICH than prognostic scales.
引用
收藏
页码:126 / 133
页数:8
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