The Continuing Plague of Extended-Spectrum β-Lactamase Producing Enterbacterales Infections An Update

被引：19

作者：

Adler, Amos ^{[1
,2
]}

Katz, David E. ^{[3
]}

Marchaim, Dror ^{[2
,4
]}

机构：

[1] Tel Aviv Sourasky Med Ctr, Clin Microbiol Lab, 6 Weizmann St, IL-6423906 Tel Aviv, Israel

[2] Tel Aviv Univ, Sackler Sch Med, Tel Aviv, Israel

[3] Shaare Zedek Med Ctr, Div Internal Med, 12 Shmuel Bait St, IL-9103102 Jerusalem, Israel

[4] Shamir Assaf Harofeh Med Ctr, Unit Infect Control, IL-7030000 Zerifin, Israel

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2020年 / 34卷 / 04期

关键词：

Gram-negative; MDRO; Escherichia coli; Klebsiella pneumoniae; Proteus mirabilis; BLOOD-STREAM INFECTIONS; URINARY-TRACT-INFECTIONS; IN-VITRO ACTIVITY; CARBAPENEM-RESISTANT ENTEROBACTERIACEAE; ESBL-PRODUCING KLEBSIELLA; SUSCEPTIBLE STAPHYLOCOCCUS-AUREUS; ESCHERICHIA-COLI INFECTION; CARE-ASSOCIATED INFECTIONS; GRAM-NEGATIVE BACTERIA; RISK-FACTORS;

D O I：

10.1016/j.idc.2020.06.003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Antimicrobial resistance is a common iatrogenic complication of modern life and medical care. One of the most demonstrative examples is the exponential increase in the incidence of extended-spectrum beta-lactamases (ESBLs) production among Enterobacteriaceae, that is, the most common human pathogens outside of the hospital setting. Infections resulting from ESBL-producing bacteria are associated with devastating outcomes, now affecting even previously healthy individuals. This poses an enormous burden and threat to public health. This article aims to narrate the evolving epidemiology of ESBL infections and highlights current challenges in terms of management and prevention of these common infections.

引用

页码：677 / +

页数：33

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