Development of a Suzuki Cross-Coupling Reaction between 2-Azidoarylboronic Pinacolate Esters and Vinyl Triflates To Enable the Synthesis of [2,3]-Fused Indole Heterocycles

被引：33
作者：
Jana, Navendu [1 ]
Quyen Nguyen [1 ]
Driver, Tom G. [1 ]
机构：
[1] Univ Illinois, Dept Chem, Chicago, IL 60607 USA
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2014年 / 79卷 / 06期
基金：
美国国家科学基金会; 美国国家卫生研究院;
关键词：
C-H AMINATION; BORONIC ACIDS; RH-2(II)-CATALYZED SYNTHESIS; REGIOSPECIFIC SYNTHESIS; CATALYZED FORMATION; ARYLBORONIC ACIDS; ORGANIC AZIDES; ARYL; CHEMISTRY; DERIVATIVES;
D O I：
10.1021/jo500252e
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The scope and limitations of a Suzuki reaction between 2-azidoarylboronic acid pinacolate esters and vinyl triflates are reported. This cross-coupling reaction enables the regioselective synthesis of indoles after a subsequent Rh-2(II)-catalyzed sp(2)-C-H bond amination reaction.
引用
收藏
页码：2781 / 2791
页数：11
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