Women and lung cancer: Clinical and molecular profiling as a determinate for treatment decisions A literature review

被引：10

作者：

Berardi, Rossana ^{[1
]}

Verdecchia, Lorena ^{[1
]}

Paolo, Marzia Di Pietro ^{[1
]}

Giampieri, Riccardo ^{[1
]}

Scartozzi, Mario ^{[1
]}

Pierantoni, Chiara ^{[1
]}

Bianconi, Maristella ^{[1
]}

Mazzanti, Paola ^{[1
]}

Cascinu, Stefano ^{[1
]}

机构：

[1] Univ Politecn Marche, Azienda Osped, Univ Osped Riuniti Umberto I, GM Lancisi,G Salesi,Clin Oncol Med, I-60020 Ancona, Italy

来源：

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 2009年 / 69卷 / 03期

关键词：

Lung cancer; NSCLC Women; Molecular biology; Target therapies; ENVIRONMENTAL TOBACCO-SMOKE; RANDOMIZED PHASE-II; PREVIOUSLY TREATED PATIENTS; VINORELBINE PLUS CISPLATIN; ENDOTHELIAL GROWTH-FACTOR; ESTROGEN-RECEPTOR-ALPHA; GENETIC POLYMORPHISMS; REPLACEMENT THERAPY; C-ERBB-2; EXPRESSION; MONOCLONAL-ANTIBODY;

D O I：

10.1016/j.critrevonc.2008.06.008

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In the past decade the incidence of lung cancer among women has risen, whereas among men it has slightly declined. Important differences in lung cancer have been demonstrated between men and women, although many areas still remain controversial. Some biologic differences may justify the increase in response of women to therapy for lung cancer and can partially explain the improved survival of women compared with men. We extensively reviewed the published scientific literature on this topic in order to investigate the clinical and genetic profiling underlying lung cancer in women and to use this information as a tool for medical therapy. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：223 / 236

页数：14

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