Triterpenoid saponins from the genus Camellia: structures, biological activities, and molecular simulation for structure-activity relationship

被引：57
作者：
Cui, Chuanjian [1 ]
Zong, Jianfa [1 ]
Sun, Yue [1 ]
Zhang, Liang [1 ]
Ho, Chi-Tang [2 ]
Wan, Xiaochun [1 ]
Hou, Ruyan [1 ]
机构：
[1] Anhui Agr Univ, Sch Tea & Food Sci & Technol, Int Joint Lab Tea Chem & Hlth Effects, State Key Lab Tea Plant Biol & Utilizat, Hefei 230036, Anhui, Peoples R China
[2] Rutgers State Univ, Food Sci Dept, 65 Dudley Rd, New Brunswick, NJ 08901 USA
来源：
FOOD & FUNCTION | 2018年 / 9卷 / 06期
关键词：
TEA SEED SAPONIN; CHAKASAPONINS I-III; CELL-CYCLE ARREST; FLOWER BUDS; OLEANANE-TYPE; BIOACTIVE SAPONINS; DEFATTED SEEDS; GASTROINTESTINAL TRANSIT; ANTIALLERGIC ACTIVITY; QUANTITATIVE-ANALYSIS;
D O I：
10.1039/c8fo00755a
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This review summarizes the isolation, chemical identification, and biochemical activities of Camellia triterpenoid saponins, updating a previous review and encompassing all new studies through September 2017. Further, molecular simulations of the interaction between several known cytotoxic oleiferasaponin monomers and Interleukin-6 are discussed, demonstrating that molecular modeling is a convenient method to obtain structure-activity information.
引用
收藏
页码：3069 / 3091
页数：23
相关论文
共 138 条
[41]   SEED SAPONIN OF THEA-SINENSIS L .1. THEA-SAPONIN AND THEA-PROSAPOGENOL [J].
ISHIDATE, M ;
UEDA, Y .
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1952, 72 (11) :1523-1524
[42]  
ITOKAWA H, 1968, Yakugaku Zasshi, V88, P1463
[43]   Noninvasive fluorescence excitation spectroscopy during application of 5-aminolevulinic acid in vivo [J].
Juzenas, P ;
Juzeniene, A ;
Kaalhus, O ;
Iani, V ;
Moan, J .
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, 2002, 1 (10) :745-748
[44]   HPLC fractionation and pharmacological assessment of green tea seed saponins for antimicrobial, anti-angiogenic and hemolytic activities [J].
Kim, Jong Deog ;
Khan, Muhammad Imran ;
Shin, Jin Hyuk ;
Lee, Moon Geon ;
Seo, Hyo Jin ;
Shin, Tai Sun ;
Kim, Min Yong .
BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, 2015, 20 (06) :1035-1043
[45]  
Kitagawa I, 1998, CHEM PHARM BULL, V46, P1901, DOI 10.1248/cpb.46.1901
[46]   Isotheasaponins B1-B3 from Camellia sinensis var. sinensis tea leaves [J].
Kobayashi, Keiko ;
Teruya, Toshiaki ;
Suenaga, Kiyotake ;
Matsui, Yoko ;
Masuda, Hideki ;
Kigoshi, Hideo .
PHYTOCHEMISTRY, 2006, 67 (13) :1385-1389
[47]   Nutrient intake, digestibility and performance of Gaddi kids supplemented with tea seed or tea seed saponin extract [J].
Kumar, M. ;
Kannan, A. ;
Bhar, R. ;
Gulati, A. ;
Gaurav, A. ;
Sharma, V. K. .
ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 2017, 30 (04) :486-494
[48]   Bioactive Saponin from Tea Seed Pomace with Inhibitory Effects against Rhizoctonia solani [J].
Kuo, Ping-Chung ;
Lin, Tsung-Chun ;
Yang, Cheng-Wei ;
Lin, Chih-Lung ;
Chen, Guo-Feng ;
Huang, Jenn-Wen .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2010, 58 (15) :8618-8622
[49]  
Li N, 2007, HETEROCYCLES, V71, P1193
[50]   Phytochemical analysis of the triterpenoids with cytotoxicity and QR inducing properties from the total tea seed saponin of Camellia sinensis [J].
Li, Ning ;
Ma, Zhong-jun ;
Chu, Yang ;
Wang, Ying ;
Li, Xian .
FITOTERAPIA, 2013, 84 :321-325
12345678910