Triterpenoid saponins from the genus Camellia: structures, biological activities, and molecular simulation for structure-activity relationship

被引：57

作者：

Cui, Chuanjian ^{[1
]}

Zong, Jianfa ^{[1
]}

Sun, Yue ^{[1
]}

Zhang, Liang ^{[1
]}

Ho, Chi-Tang ^{[2
]}

Wan, Xiaochun ^{[1
]}

Hou, Ruyan ^{[1
]}

机构：

[1] Anhui Agr Univ, Sch Tea & Food Sci & Technol, Int Joint Lab Tea Chem & Hlth Effects, State Key Lab Tea Plant Biol & Utilizat, Hefei 230036, Anhui, Peoples R China

[2] Rutgers State Univ, Food Sci Dept, 65 Dudley Rd, New Brunswick, NJ 08901 USA

来源：

FOOD & FUNCTION | 2018年 / 9卷 / 06期

关键词：

TEA SEED SAPONIN; CHAKASAPONINS I-III; CELL-CYCLE ARREST; FLOWER BUDS; OLEANANE-TYPE; BIOACTIVE SAPONINS; DEFATTED SEEDS; GASTROINTESTINAL TRANSIT; ANTIALLERGIC ACTIVITY; QUANTITATIVE-ANALYSIS;

D O I：

10.1039/c8fo00755a

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review summarizes the isolation, chemical identification, and biochemical activities of Camellia triterpenoid saponins, updating a previous review and encompassing all new studies through September 2017. Further, molecular simulations of the interaction between several known cytotoxic oleiferasaponin monomers and Interleukin-6 are discussed, demonstrating that molecular modeling is a convenient method to obtain structure-activity information.

引用

页码：3069 / 3091

页数：23