HIV Infection and Depression Among Opiate Users in a US Epicenter of the Opioid Epidemic

被引：11

作者：

Denis, Cecile M. ^{[1
]}

Dominique, Tiffany ^{[1
]}

Smith, Peter ^{[1
]}

Fiore, Danielle ^{[1
]}

Ku, Yi-Chien ^{[1
]}

Culhane, Angus ^{[1
]}

Dunbar, Debora ^{[1
]}

Brown, Dana ^{[1
]}

Daramay, Menvekeh ^{[1
]}

Voytek, Chelsea ^{[1
]}

Morales, Knashawn H. ^{[2
]}

Blank, Michael B. ^{[1
]}

Crits-Christoph, Paul F. ^{[1
]}

Douglas, Steven D. ^{[4
]}

Spitsin, Serguei ^{[4
]}

Frank, Ian ^{[3
]}

Colon-Rivera, Krystal ^{[5
]}

Montaner, Luis J. ^{[5
]}

Metzger, David S. ^{[1
]}

Evans, Dwight L. ^{[1
]}

机构：

[1] Univ Penn, Dept Psychiat, Perelman Sch Med, 3535 Market St,Suite 4000, Philadelphia, PA 19104 USA

[2] Univ Penn, Dept Biostat Epidemiol & Informat, Perelman Sch Med, Philadelphia, PA 19104 USA

[3] Univ Penn, Dept Med, Perelman Sch Med, Philadelphia, PA 19104 USA

[4] Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA

[5] Wistar Inst Anat & Biol, 3601 Spruce St, Philadelphia, PA 19104 USA

来源：

AIDS AND BEHAVIOR | 2021年 / 25卷 / 07期

关键词：

Opioid; HIV; Risk behavior; Depression; MOUD; INVOLVED OVERDOSE DEATHS; 16-ITEM QUICK INVENTORY; SUBSTANCE USE DISORDERS; UNITED-STATES; INJECT DRUGS; HEPATITIS-C; BEHAVIORS; SYMPTOMATOLOGY; INTERVENTIONS; COMORBIDITY;

D O I：

10.1007/s10461-020-03151-2

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Using a mobile research facility, we enrolled 141 opioid users from a neighborhood of Philadelphia, an urban epicenter of the opioid epidemic. Nearly all (95.6%) met DSM-5 criteria for severe opioid use disorder. The prevalence of HIV infection (8.5%) was more than seven times that found in the general population of the city. Eight of the HIV-positive participants (67.0%) reported receiving antiretroviral treatment but almost all of them had unsuppressed virus (87.5%). The majority of participants (57.4%) reported symptoms consistent with major depressive disorder. Severe economic distress (60.3%) and homelessness were common (57%). Polysubstance use was nearly universal, 72.1% had experienced multiple overdoses and prior medication for opioid use disorder (MOUD) treatment episodes (79.9%), but few currently engaged in addiction care. The prevalence, multiplicity and severity of chronic health and socioeconomic problems highlight consequences of the current opioid epidemic and underscore the urgent need to develop integrated models of treatment.

引用

页码：2230 / 2239

页数：10

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