Diagnostic accuracy of coronary CT angiography using 3rd-generation dual-source CT and automated tube voltage selection: Clinical application in a non-obese and obese patient population

To investigate diagnostic accuracy of 3(rd)-generation dual-source CT (DSCT) coronary angiography in obese and non-obese patients. We retrospectively analyzed 76 patients who underwent coronary CT angiography (CCTA) and invasive coronary angiography. Prospectively ECG-triggered acquisition was performed with automated tube voltage selection (ATVS). Patients were dichotomized based on body mass index in groups A (< 30 kg/m(2), n = 37) and B (a 30 kg/m(2), n = 39) and based on tube voltage in groups C (< 120 kV, n = 46) and D (120 kV, n = 30). Coronary arteries were assessed for significant stenoses (a 50 % luminal narrowing) and diagnostic accuracy was calculated. Per-patient overall sensitivity, specificity, positive predictive value, negative predictive value (NPV) and accuracy were 96.9 %, 95.5 %, 93.9 %, 97.7 % and 96.1 %, respectively. Sensitivity and NPV were lower in groups B and D compared to groups A and C, but no statistically significant differences were observed (group A vs. B: sensitivity, 100.0 % vs. 93.3 %, p = 0.9493; NPV, 100 % vs. 95.5 %, p = 0.9812; group C vs. D: sensitivity, 100.0 % vs. 92.3 %, p = 0.8462; NPV, 100.0 % vs. 94.1 %, p = 0.8285). CCTA using 3(rd)-generation DSCT and (ATVS) provides high diagnostic accuracy in both non-obese and obese patients. aEuro cent Coronary CTA provides high diagnostic accuracy in non-obese and obese patients. aEuro cent Diagnostic accuracy between obese and non-obese patients showed no significant difference. aEuro cent < 120 kV studies were performed in 44 % of obese patients. aEuro cent Current radiation dose-saving approaches can be applied independent of body habitus.