Vaccination against infectious diseases: What is promising?

被引：14

作者：

Doerr, Hans Wilhelm ^{[1
]}

Berger, Annemarie ^{[1
]}

机构：

[1] Goethe Univ Frankfurt, Univ Hosp Frankfurt, Inst Med Virol, D-60596 Frankfurt, Germany

来源：

MEDICAL MICROBIOLOGY AND IMMUNOLOGY | 2014年 / 203卷 / 06期

关键词：

Vaccines; Passive immunisation; Adoptive transfer of lymphocytes; Hepatitis virus; Influenza virus; Herpes viruses; HIV; Tuberculosis; Diphtheria; Tetanus; Oncogenic HPV; INFLUENZA-A H5N1; HEPATITIS-B; AVIAN INFLUENZA; HUMAN-PAPILLOMAVIRUS; VIRUS; VACCINES; PREVALENCE; ANTIBODIES; HIV; CHILDREN;

D O I：

10.1007/s00430-014-0346-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Vaccination has proven to be one of the best weapons protecting the mankind against infectious diseases. Along with the huge progress in microbiology, numerous highly efficacious and safe vaccines have been produced by conventional technology (cultivation), by the use of molecular biology (genetic modification), or by synthetic chemistry. Sterilising prevention is achieved by the stimulation of antibody production, while the stimulation of cell-mediated immune responses may prevent the outbreak of disease in consequence of an acute or reactivated infection. From several examples, two rules are deduced to evaluate the perspectives of future vaccine developments: They are promising, if (1) the natural infectious disease induces immunity or (2) passive immunisation (transfer of antibodies, adoptive transfer of lymphocytes) is successful in preventing infection.

引用

页码：365 / 371

页数：7

共 82 条

[1] HIV-1 progression links with viral genetic variability and subtype, and patient's HLA type: analysis of a Nairobi-Kenyan cohort [J].

Abidi, Syed Hani ;

Shahid, Aniqa ;

Lakhani, Laila S. ;

Shah, Reena ;

Okinda, Nancy ;

Ojwang, Peter ;

Abbas, Farhat ;

Rowland-Jones, Sarah ;

Ali, Syed .

MEDICAL MICROBIOLOGY AND IMMUNOLOGY, 2014, 203 (01) :57-63

[2] Trivalent influenza vaccination of healthy adults 3 years after the onset of swine-origin H1N1 pandemic: restricted immunogenicity of the new A/H1N1v constituent? [J].

Allwinn, R. ;

Bickel, M. ;

Lassmann, C. ;

Wicker, S. ;

Friedrichs, I. .

MEDICAL MICROBIOLOGY AND IMMUNOLOGY, 2013, 202 (02) :125-130

[3] Comparison of seasonal influenza vaccines: composition and properties [J].

Allwinn, R. ;

Doerr, H. W. .

DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 2011, 136 (45) :2315-2318

[4] Molecular epidemiology of HIV in a cohort of men having sex with men from Istanbul [J].

Alpsar, Dilek ;

Agacfidan, Ali ;

Luebke, Nadine ;

Verheyen, Jens ;

Eraksoy, Haluk ;

Cagatay, Atahan ;

Bozkaya, Emel ;

Kaiser, Rolf ;

Akguel, Baki .

MEDICAL MICROBIOLOGY AND IMMUNOLOGY, 2013, 202 (03) :251-255

[5] A vaccine against serogroup B Neisseria meningitidis: dealing with uncertainty [J].

Andrews, Sophie M. ;

Pollard, Andrew .

LANCET INFECTIOUS DISEASES, 2014, 14 (05) :426-434

[6] The past, present and future of neutralizing antibodies for hepatitis C virus [J].

Ball, Jonathan K. ;

Tarr, Alexander W. ;

McKeating, Jane A. .

ANTIVIRAL RESEARCH, 2014, 105 :100-111

[7] Neuraminidase inhibitor susceptibility of swine influenza A viruses isolated in Germany between 1981 and 2008 [J].

Bauer, Katja ;

Duerrwald, Ralf ;

Schlegel, Michael ;

Pfarr, Kathrin ;

Topf, Dominik ;

Wiesener, Nadine ;

Dahse, Hans-Martin ;

Wutzler, Peter ;

Schmidtke, Michaela .

MEDICAL MICROBIOLOGY AND IMMUNOLOGY, 2012, 201 (01) :61-72

[8] Possible hidden hazards of mass vaccination against new influenza A/H1N1: have the cardiovascular risks been adequately weighed? [J].

Bhakdi, Sucharit ;

Lackner, Karl ;

Doerr, Hans-Wilhelm .

MEDICAL MICROBIOLOGY AND IMMUNOLOGY, 2009, 198 (04) :205-209

[9] Immune Response after a Single Dose of the 2010/11 Trivalent, Seasonal Influenza Vaccine in HIV-1-Infected Patients and Healthy Controls [J].

Bickel, Markus ;

Lassmann, Christin ;

Wieters, Imke ;

Doerr, Hans Wilhelm ;

Herrmann, Eva ;

Wicker, Sabine ;

Brodt, Hans Reinhard ;

Stephan, Christoph ;

Allwinn, Regina ;

Jung, Oliver .

HIV CLINICAL TRIALS, 2013, 14 (04) :175-181

[10] N-terminal myristoylation-dependent masking of neutralizing epitopes in the preS1 attachment site of hepatitis B virus [J].

Bremer, Corinna M. ;

Sominskaya, Irina ;

Skrastina, Dace ;

Pumpens, Paul ;

Abd El Wahed, Ahmed ;

Beutling, Ulrike ;

Frank, Ronald ;

Fritz, Hans-Joachim ;

Hunsmann, Gerhard ;

Gerlich, Wolfram H. ;

Glebe, Dieter .

JOURNAL OF HEPATOLOGY, 2011, 55 (01) :29-37

← 1 2 3 4 5 6 7 8 9 →