Chiral Resolution using Supramolecular-Templated Mesostructured Materials

被引：21
|
作者：
Huang, Yanan [1 ]
Vidal, Xavier [1 ,2 ]
Garcia-Bennett, Alfonso E. [1 ,3 ]
机构：
[1] Macquarie Univ, Dept Mol Sci, Sydney, NSW 2109, Australia
[2] Macquarie Univ, Dept Phys & Astron, Sydney, NSW 2109, Australia
[3] Macquarie Univ, Australian Res Council, Ctr Nanoscale Biophoton, Sydney, NSW 2109, Australia
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2019年 / 58卷 / 32期
基金：
澳大利亚研究理事会;
关键词：
chirality; mesoporous materials; self-assembly; separation; supramolecular chemistry; TRANSCRIPTION; NANOPARTICLES; MECHANISM;
D O I：
10.1002/anie.201900950
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Chiral resolution using non-functionalized mesoporous particles is demonstrated for a variety of enantiomeric pairs. This is achieved through the use of supramolecular templated silica materials prepared with guanosine monophosphate (NGM-1) and folic acid (NFM-1) which enable direct chiral transcription onto the surface of the mesopores after solvent extraction and post calcination of the template. The chiral selectivity and kinetics of the mesoporous materials are measured by circular dichroism (CD) spectroscopy on adsorbed molecules with different affinities for the pore surface. NGM-1 and NFM-1 have opposite enantiomeric selectivity for enantiomeric pairs. These results significantly increase the potential of mesoporous materials for chiral separation and enantiomeric catalysis.
引用
收藏
页码：10859 / 10862
页数：4
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