Controlled-Release Systems for Metal-Based Nanomedicine: Encapsulated/Self-Assembled Nanoparticles of Anticancer Gold(III)/Platinum(II) Complexes and Antimicrobial Silver Nanoparticles

被引：73

作者：

Lok, Chun-Nam ^{[1
,2
]}

Zou, Taotao ^{[1
,2
]}

Zhang, Jing-Jing ^{[1
,2
]}

Lin, Iris Wing-Shan ^{[1
,2
]}

Che, Chi-Ming ^{[1
,2
,3
]}

机构：

[1] Univ Hong Kong, Inst Mol Funct Mat, State Key Lab Synthet Chem, Hong Kong, Hong Kong, Peoples R China

[2] Univ Hong Kong, Dept Chem, Hong Kong, Hong Kong, Peoples R China

[3] HKU Shenzhen Inst Res & Innovat, Shenzhen 518053, Peoples R China

来源：

ADVANCED MATERIALS | 2014年 / 26卷 / 31期

关键词：

SUPRAMOLECULAR POLYMERS; ANTIBACTERIAL ACTIVITY; NANOSILVER; TOXICITY; DELIVERY; HYDROGELATION; NANOCARRIERS; DISSOLUTION; NANOFIBERS; IONS;

D O I：

10.1002/adma.201305617

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The therapeutic applications of many anticancer or antimicrobial metal complexes often suffer from low solubility and low stability in physiological conditions or from drug resistance. To circumvent these problems, nanoparticle systems that allow controlled release and specific accumulation in the targeted disease tissue are of advantage for efficient treatment with minimal toxicity. The focus of this Research News is metal-based nanomaterials comprising anticancer gold(III)/platinum(II) complexes or antimicrobial silver, highlighting the controlled-release properties of self-assembled metal systems.

引用

页码：5550 / 5557

页数：8

共 46 条

[1] Bioavailability of silver nanoparticles and ions: from a chemical and biochemical perspective [J].

Behra, Renata ;

Sigg, Laura ;

Clift, Martin J. D. ;

Herzog, Fabian ;

Minghetti, Matteo ;

Johnston, Blair ;

Petri-Fink, Alke ;

Rothen-Rutishauser, Barbara .

JOURNAL OF THE ROYAL SOCIETY INTERFACE, 2013, 10 (87)

[2] Bacterial Killing by Light-Triggered Release of Silver from Biomimetic Metal Nanorods [J].

Black, Kvar C. L. ;

Sileika, Tadas S. ;

Yi, Ji ;

Zhang, Ran ;

Rivera, Jose G. ;

Messersmith, Phillip B. .

SMALL, 2014, 10 (01) :169-178

[3]

Boulikas T., 2007, CANC THERAPY, V5, P351

[4]

Chapman J, 2012, RSC NANOSCI NANOTECH, P1, DOI 10.1039/9781849735261

[5] Therapeutic applications of gold complexes: lipophilic gold(III) cations and gold(I) complexes for anti-cancer treatment [J].

Che, Chi-Ming ;

Sun, Raymond Wai-Yin .

CHEMICAL COMMUNICATIONS, 2011, 47 (34) :9554-9560

[6] Silver as Antibacterial Agent: Ion, Nanoparticle, and Metal [J].

Chernousova, Svitlana ;

Epple, Matthias .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 52 (06) :1636-1653

[7] Therapeutic nanoparticles for drug delivery in cancer [J].

Cho, Kwangjae ;

Wang, Xu ;

Nie, Shuming ;

Chen, Zhuo ;

Shin, Dong M. .

CLINICAL CANCER RESEARCH, 2008, 14 (05) :1310-1316

[8] Ultrastable silver nanoparticles [J].

Desireddy, Anil ;

Conn, Brian E. ;

Guo, Jingshu ;

Yoon, Bokwon ;

Barnett, Robert N. ;

Monahan, Bradley M. ;

Kirschbaum, Kristin ;

Griffith, Wendell P. ;

Whetten, Robert L. ;

Landman, Uzi ;

Bigioni, Terry P. .

NATURE, 2013, 501 (7467) :399-402

[9] Nanobio Silver: Its Interactions with Peptides and Bacteria, and Its Uses in Medicine [J].

Eckhardt, Sonja ;

Brunetto, Priscilla S. ;

Gagnon, Jacinthe ;

Priebe, Magdalena ;

Giese, Bernd ;

Fromm, Katharina M. .

CHEMICAL REVIEWS, 2013, 113 (07) :4708-4754

[10] Generation of Metal Nanoparticles from Silver and Copper Objects: Nanoparticle Dynamics on Surfaces and Potential Sources of Nanoparticles in the Environment [J].

Glover, Richard D. ;

Miller, John M. ;

Hutchison, James E. .

ACS NANO, 2011, 5 (11) :8950-8957

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