Is medical therapy useful in the management of stress urinary incontinence?

被引：0

作者：

Oelke, M. ^{[1
]}

Seidler, M. ^{[1
]}

Ueckert, S. ^{[1
]}

Gabuev, A. ^{[1
]}

机构：

[1] Hannover Med Sch, Klin Urol & Urol Onkol, D-30625 Hannover, Germany

来源：

UROLOGE | 2009年 / 48卷 / 03期

关键词：

Stress urinary incontinence; Medical treatment; Duloxetine; Serotonin; Noradrenaline; DULOXETINE; WOMEN; EFFICACY; SAFETY;

D O I：

10.1007/s00120-008-1917-9

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

In Germany, only duloxetine is registered for treating stress urinary incontinence in adult women; duloxetine treatment for stress urinary incontinence in children or men is poorly investigated and still off-label. Trials in women based on the evidence level 1B and meta-analyses have demonstrated that duloxetine significantly reduced the frequency of incontinence episodes and increased incontinence-related quality of life. However, duloxetine must be used on a regular base to maintain these positive effects. Therefore, duloxetine seems to be especially indicated in women who refuse or cannot be subjected to physical or surgical treatment and are willing to accept the long-term use and possible side effects of the drug. Furthermore, duloxetine could be useful in women to support pelvic floor physiotherapy or in female patients awaiting incontinence surgery.

引用

页码：228 / +

页数：4

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