Neighborhood disadvantage and racial disparities in colorectal cancer incidence: a population-based study in Louisiana

被引：19
作者：
Danos, Denise M. [1 ]
Ferguson, Tekeda F. [1 ,2 ]
Simonsen, Neal R. [1 ]
Leonardi, Claudia [1 ,3 ]
Yu, Qingzhao [1 ,4 ]
Wu, Xiao-Cheng [2 ,5 ]
Scribner, Richard A. [1 ,2 ]
机构：
[1] Louisiana State Univ Hlth New Orleans, Stanley S Scott Canc Ctr, Sch Med, New Orleans, LA USA
[2] Louisiana State Univ Hlth New Orleans, Sch Publ Hlth, Dept Epidemiol, New Orleans, LA USA
[3] Louisiana State Univ Hlth New Orleans, Sch Publ Hlth, Dept Community & Behav Hlth, New Orleans, LA USA
[4] Louisiana State Univ Hlth New Orleans, Sch Publ Hlth, Dept Biostat, New Orleans, LA USA
[5] Louisiana State Univ Hlth New Orleans, Sch Publ Hlth, Louisiana Tumor Registry, New Orleans, LA USA
来源：
ANNALS OF EPIDEMIOLOGY | 2018年 / 28卷 / 05期
基金：
美国国家卫生研究院;
关键词：
Colorectal cancer; Concentrated disadvantage; Disparities; Multilevel modeling; Social epidemiology; SOCIOECONOMIC-STATUS; HEALTH DISPARITIES; UNITED-STATES; MORTALITY; POVERTY; STRESS; RISK; ASSOCIATIONS; INFLAMMATION; ENVIRONMENT;
D O I：
10.1016/j.annepidem.2018.02.004
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Purpose: Colorectal cancer (CRC) continues to demonstrate racial disparities in incidence and survival in the United States. This study investigates the role of neighborhood concentrated disadvantage in racial disparities in CRC incidence in Louisiana. Methods: Louisiana Tumor Registry and U.S. Census data were used to assess the incidence of CRC diagnosed in individuals 35 years and older between 2008 and 2012. Neighborhood concentrated disadvantage index (CDI) was calculated based on the PhenX Toolkit protocol. The incidence of CRC was modeled using multilevel binomial regression with individuals nested within neighborhoods. Results: Our study included 10,198 cases of CRC. Adjusting for age and sex, CRC risk was 28% higher for blacks than whites (risk ratio [RR] = 1.28; 95% confidence interval [CI] = 1.22-1.33). One SD increase in CDI was associated with 14% increase in risk for whites (RR = 1.14; 95% CI = 1.10-1.18) and 5% increase for blacks (RR = 1.05; 95% CI = 1.02-1.09). After controlling for differential effects of CDI by race, racial disparities were not observed in disadvantaged areas. Conclusion: CRC incidence increased with neighborhood disadvantage and racial disparities diminished with mounting disadvantage. Our results suggest additional dimensions to racial disparities in CRC outside of neighborhood disadvantage that warrants further research. (C) 2018 Elsevier Inc. All rights reserved.
引用
收藏
页码：316 / 321
页数：6
相关论文
共 41 条
  • [1] Colonoscopy Is Associated With a Reduced Risk for Colon Cancer and Mortality in Patients With Inflammatory Bowel Diseases
    Ananthakrishnan, Ashwin N.
    Cagan, Andrew
    Cai, Tianxi
    Gainer, Vivian S.
    Shaw, Stanley Y.
    Churchill, Susanne
    Karlson, Elizabeth W.
    Murphy, Shawn N.
    Kohane, Isaac
    Liao, Katherine P.
    [J]. CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2015, 13 (02) : 322 - U163
  • [2] [Anonymous], 2013, CANC FACTS FIG AFR A
  • [3] Parameter estimation and goodness-of-fit in log binomial regression
    Blizzard, L
    Hosmer, DW
    [J]. BIOMETRICAL JOURNAL, 2006, 48 (01) : 5 - 22
  • [4] CDC, 2017, CRCCP
  • [5] Racial differences in neighborhood disadvantage, inflammation and metabolic control in black and white pediatric type 1 diabetes patients
    Coulon, Sara J.
    Velasco-Gonzalez, Cruz
    Scribner, Richard
    Park, Chi L.
    Gomez, Ricardo
    Vargas, Alfonso
    Stender, Sarah
    Zabaleta, Jovanny
    Clesi, Patrice
    Chalew, Stuart A.
    Hempe, James M.
    [J]. PEDIATRIC DIABETES, 2017, 18 (02) : 120 - 127
  • [6] Socioeconomic status and the risk of colorectal cancer An Analysis of More Than a Half Million Adults in the National Institutes of Health-AARP Diet and Health Study
    Doubeni, Chyke A.
    Laiyemo, Adeyinka O.
    Major, Jacqueline M.
    Schootman, Mario
    Lian, Min
    Park, Yikyung
    Graubard, Barry I.
    Hollenbeck, Albert R.
    Sinha, Rashmi
    [J]. CANCER, 2012, 118 (14) : 3636 - 3644
  • [7] Neighborhood Characteristics and Availability of Healthy Foods in Baltimore
    Franco, Manuel
    Roux, Ana V. Diez
    Glass, Thomas A.
    Caballero, Benjamin
    Brancati, Frederick L.
    [J]. AMERICAN JOURNAL OF PREVENTIVE MEDICINE, 2008, 35 (06) : 561 - 567
  • [8] Geography UCB, 2012, GEOGR AR REF MAN
  • [9] Weathering and age patterns of allostatic load scores among blacks and whites in the United States
    Geronimus, AT
    Hicken, M
    Keene, D
    Bound, J
    [J]. AMERICAN JOURNAL OF PUBLIC HEALTH, 2006, 96 (05) : 826 - 833
  • [10] The impact of neighborhood social and built environment factors across the cancer continuum: Current research, methodological considerations, and future directions
    Gomez, Scarlett Lin
    Shariff-Marco, Salma
    DeRouen, Mindy
    Keegan, Theresa H. M.
    Yen, Irene H.
    Mujahid, Mahasin
    Satariano, William A.
    Glaser, Sally L.
    [J]. CANCER, 2015, 121 (14) : 2314 - 2330
12345