Interactions between nitric oxide, oxygen, reactive oxygen species and reactive nitrogen species

被引：46

作者：

Brown, G. C. ^{[1
]}

Borutaite, V. ^{[1
]}

机构：

[1] Univ Cambridge, Dept Biochem, Cambridge CB2 1QW, England

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 2006年 / 34卷

关键词：

cell death; mitochondrion; peroxynitrite; reactive nitrogen species; reactive oxygen species; HYDROGEN-PEROXIDE; NADPH OXIDASE; SUPEROXIDE-DISMUTASE; COMPLEX-I; PEROXYNITRITE; INHIBITION; PROLIFERATION; GENERATION; SYNTHASES; APOPTOSIS;

D O I：

10.1042/BST0340953

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

ROS (reactive oxygen species) and RNS (reactive nitrogen species) are central to the innate immunity that protects us from infection, but also contribute to degenerative diseases and possibly aging. However, ROS and RNS are increasingly recognized to contribute to physiological signalling. This review briefly describes the main interactions between ROS and RNS and shows how their origins, chemistry, metabolism and biological actions are intimately linked.

引用

页码：953 / 956

页数：4

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