Synthesis of chiral oxazolidin-2-ones by 1,2-amino alcohols, carbon dioxide and electrogenerated acetonitrile anion

被引：52
作者：
Feroci, M
Gennaro, A
Inesi, A
Orsini, M
Palombi, L
机构：
[1] Univ Roma La Sapienza, Dip Ingn Chim Mat Materie Prime & Met, I-00161 Rome, Italy
[2] Univ Aquila, Dipartimento Chim Ingn Chim & Mat, I-67040 Laquila, Italy
[3] Univ Padua, Dept Phys Chem, I-35131 Padua, Italy
来源：
TETRAHEDRON LETTERS | 2002年 / 43卷 / 33期
关键词：
electrochemistry; oxazolidin-2-ones; carbon dioxide;
D O I：
10.1016/S0040-4039(02)01186-3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An improved electrochemical synthesis of chiral oxazolidin-2-ones from chiral 1,2-amino alcohols is obtained by direct electrolysis of solutions of MeCN TEAP containing the amino alcohol, with subsequent CO2 bubbling and addition of TsCl. This synthesis avoids any addition of bases or probases and yields oxazolidinones in high yields. (C) 2002 Elsevier Science Ltd. All rights reserved.
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收藏
页码：5863 / 5865
页数：3
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