Effect of probe geometry and optical properties on the sampling depth for diffuse reflectance spectroscopy

被引：40

作者：

Hennessy, Ricky ^{[1
]}

Goth, Will ^{[1
]}

Sharma, Manu ^{[1
]}

Markey, Mia K. ^{[1
,2
]}

Tunnell, James W. ^{[1
]}

机构：

[1] Univ Texas Austin, Austin, TX 78712 USA

[2] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

来源：

JOURNAL OF BIOMEDICAL OPTICS | 2014年 / 19卷 / 10期

关键词：

diffuse reflectance spectroscopy; sampling depth; Monte Carlo; MONTE-CARLO; TURBID MEDIA; IN-VIVO; PENETRATION DEPTH; LIGHT TRANSPORT; SKIN; ILLUMINATION; MODEL;

D O I：

10.1117/1.JBO.19.10.107002

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The sampling depth of light for diffuse reflectance spectroscopy is analyzed both experimentally and computationally. A Monte Carlo (MC) model was used to investigate the effect of optical properties and probe geometry on sampling depth. MC model estimates of sampling depth show an excellent agreement with experimental measurements over a wide range of optical properties and probe geometries. The MC data are used to define a mathematical expression for sampling depth that is expressed in terms of optical properties and probe geometry parameters. (C) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License.

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页数：6

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