Photoinduced electron transfer between non-native donor-acceptor moieties incorporated in synthetic polypeptide aggregates

被引：54

作者：

Jones, G

Vullev, VI

机构：

[1] Boston Univ, Dept Chem, Boston, MA 02215 USA

[2] Boston Univ, Photon Ctr, Boston, MA 02215 USA

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 23期

关键词：

D O I：

10.1021/ol026656+

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A series of analogous photoactive polypeptides that form helical homo and hetero aggregates in aqueous media were prepared. A pyrenyl ketone (the principal chromophore and an electron acceptor) was attached to the N-termini. An electron donor, amidoethylcarbazole, was introduced as a side chain of a non-native amino acid, NCb, 14 residues away. Photoinduced electron-transfer rate constants of the order of 10(8) s(-1) between remote pyrene and carbazole were measured.

引用

收藏

页码：4001 / 4004

页数：4

相关论文

共 23 条

[1] ELECTROCHEMICAL AND SPECTROSCOPIC PROPERTIES OF CATION RADICALS .3. REACTION PATHWAYS OF CARBAZOLIUM RADICAL IONS [J].

AMBROSE, JF ;

CARPENTER, LL ;

NELSON, RF .

JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 1975, 122 (07) :876-894

[2] Fluorescence properties of 1-heptanoylpyrene:: a probe for hydrogen bonding in microaggregates and biological membranes [J].

Armbruster, C ;

Knapp, M ;

Rechthaler, K ;

Schamschule, R ;

Parusel, ABJ ;

Köhler, G ;

Wehrmann, W .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 1999, 125 (1-3) :29-38

[3] Electron transfer mechanisms [J].

Beratan, DN ;

Skourtis, SS .

CURRENT OPINION IN CHEMICAL BIOLOGY, 1998, 2 (02) :235-243

[4] A fluorescence assay for leucine zipper dimerization: Avoiding unintended consequences of fluorophore attachment [J].

Daugherty, DL ;

Gellman, SH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (18) :4325-4333

[5]

DEMAS JN, 1971, J PHYS CHEM-US, V75, P991, DOI 10.1021/j100678a001

[6] Electric field effects on electron transfer rates in dichromophoric peptides: The effect of helix unfolding [J].

Fox, MA ;

Galoppini, E .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (23) :5277-5285

[7] UNEQUIVOCAL DETERMINATION BY FLUORESCENCE SPECTROSCOPY OF THE FORMATION OF A PARALLEL LEUCINE-ZIPPER HOMODIMER [J].

GARCIAECHEVERRIA, C .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (13) :6031-6032

[8] A SWITCH BETWEEN 2-STRANDED, 3-STRANDED AND 4-STRANDED COILED COILS IN GCN4 LEUCINE-ZIPPER MUTANTS [J].

HARBURY, PB ;

ZHANG, T ;

KIM, PS ;

ALBER, T .

SCIENCE, 1993, 262 (5138) :1401-1407

[9] STROBOSCOPIC OPTICAL BOXCAR TECHNIQUE FOR THE DETERMINATION OF FLUORESCENCE LIFETIMES [J].

JAMES, DR ;

SIEMIARCZUK, A ;

WARE, WR .

REVIEW OF SCIENTIFIC INSTRUMENTS, 1992, 63 (02) :1710-1716

[10] FLUORESCENCE PROPERTIES OF COUMARIN LASER-DYES IN AQUEOUS POLYMER MEDIA - CHROMOPHORE ISOLATION IN POLY(METHACRYLIC ACID) HYPERCOILS [J].

JONES, G ;

RAHMAN, MA .

JOURNAL OF PHYSICAL CHEMISTRY, 1994, 98 (49) :13028-13037