The societal opportunities and challenges of genome editing

被引：40
作者：
Carroll, Dana [1 ]
Charo, R. Alta [2 ,3 ]
机构：
[1] Univ Utah, Sch Med, Dept Biochem, Salt Lake City, UT 84112 USA
[2] Univ Wisconsin, Sch Law, Madison, WI 53706 USA
[3] Univ Wisconsin, Sch Med & Publ Hlth, Dept Med Hist & Bioeth, Madison, WI 53706 USA
来源：
GENOME BIOLOGY | 2015年 / 16卷
关键词：
CRISPR-Cas; ethical issues; Food and Drug Administration; genetically engineered organism; germline genome editing; regulation; PROGRAMMABLE NUCLEASES; GENE-THERAPY; CRISPR-CAS9; MUTATIONS; RHESUS; MONKEY;
D O I：
10.1186/s13059-015-0812-0
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The genome editing platforms currently in use have revolutionized the field of genetics. At an accelerating rate, these tools are entering areas with direct impact on human well being. Here, we discuss applications in agriculture and in medicine, and examine some associated societal issues.
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页数：9
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